Successful cryopreservation of bone marrow in situ within vertebral bodies offers an opportunity for quick and convenient storage of a significant quantity of bone marrow stem cells, including hematopoietic- and mesenchymal-type stem cells. However, cryopreservation of more complex large tissues and organs, such as the vertebral body (VB), remains problematic....
Unpaved roads are sources of chronic sediment in forested watersheds. Bare soil on roads is exposed to erosion from rainfall and runoff Published research on sediment production from forest roads focuses primarily on road characteristics. Since water drives the mechanics of sediment transport, hydrologic variables should correlate with sediment production....
Paper microfluidic devices are capable of processing fluids using capillary flow in materials that are lower cost than the standard materials used in microfluidics. Due to the low cost of their fabrication and minimal requirements for instrumentation, paper microfluidic devices are ideal for use in low-resource settings. They have the...
The use of ureolytic bacteria for the remediation of contaminated groundwater aquifers by inducing calcium carbonate precipitation is being studied in order to establish a better understanding of the modeling and prediction of how the bacteria will act in situ. This research has pursued the use of various ureolytic bacteria...
The improvement of coupled tendon transfer surgeries through the insertion of an adaptive engineering mechanism was explored using biomechanical simulations performed in OpenSim. Tendon transfer surgeries are commonly performed on the upper extremity to restore hand function. A conventional 4-tailed tendon transfer procedure model and a modified 4-tailed procedure model...
Surface patterning of bacterial biofilm provides an opportunity to understand the microbial metabolic exchange between bacterial species. By using various techniques, one can put different bacterial species in close proximity and study their interaction by using various assay kits and analytical techniques. In this study, surface patterning of Pseudomonas aeruginosa...
Cytoplasmic dynein is a motor protein complex found in eukaryotes that is essential to many cellular processes. With dynein being involved in mitosis, axonal transport and organelle transport, disruption of dynein function can lead to neurodegeneration and other diseases. The main function of dynein is transportation of cargo through the...
Loss of a limb can severely impact everyday way of life. Prosthetics provide a way to return functionality to the user and improve quality of life. However, most prosthetic systems currently available in the market lack sensory feedback making them comparatively more difficult to use resulting in prosthetic abandonment. Therefore,...
Infections in hospitals account for over 100,000 deaths per year. These infections occur at the
hospital from complications following bacterial adhesion to intravenous catheters, coronary
stents and other implanted devices. Another common problem is protein adsorption to the
surface of the device and subsequent blood clotting. Methods for combating these...
The matrisome is an ensemble of genes that are highly relevant for characterizing the behavior of the extracellular matrix (ECM) during the onset and progression of many diseases. Recent advances in the definition of the matrisome, such as The Matrisome Project, have been instrumental in making more advanced resources available...