Aging is a process that all living species experiences and it also is greatly to study and understand the aging process with the aim of extending human life span. Protein homeostasis is one of the main hall mark of aging. Based on previous data, it observed that cells from long...
Marine mammals use acoustics for many life functions, including communication. Male fin whales produce a call around 20 Hz and the pattern of a series of calls can vary based on the individual, geographic region, and season. I examined the variation between songs in fin whales. A glider was deployed...
Biomass pretreatment-derived degradation compounds, such as furfural and 5-hydroxymethyl-furfural (HMF),inhibit the growth of fermentation microorganisms that utilize biomass to produce biofuels and chemicals. Here we report that manganese(III) can degrade furfural and HMF, making them less toxic to microorganisms. Treatment with manganese(III) reduced furfural and HMF concentrations in a dose-dependent...
Increased coastal development poses a potential threat to nearshore habitats in Alaska, and artificial reefs (AR) are an increasingly popular tool for mitigating habitat loss. Although well studied in tropical and temperate locations, less is known about AR efficacy in high latitude locations. Since ARs are heavily influenced by ecological...
Prostate cancer is the most common cancer among men in the United States. There are an estimated 115,024 incident cases so far in 2017. Risk factors for prostate cancer include age, black race, and family history of prostate cancer. In addition, healthful diet and lifestyle may affect risk of prostate...
Many western river systems have become degraded or incised over time due to grazing, agriculture, impoundments, and extermination of beaver. Restoration efforts are looking to more natural solutions aimed at reconnecting streams to their original floodplain. Beavers were the original ecosystem engineers in Northwest America. They built dams, which held...
Over half of the U.S. coastline is found in Alaska, and the majority of the state’s economic activity occurs along the coast. Increased coastal development poses a potential threat to nearshore habitats in Alaska. The installation of artificial reef (AR) systems can mitigate habitat loss; however, few AR systems have...
This thesis looks at the third harmonic voltage response of a small incandescent lightbulb. The third harmonic voltage, or 3 omega (3ω) voltage, arises from applying a 1ω sinusoidal voltage across a resistive material. The 3ω voltage carries with it information about the thermal conductivity of the material. A lock-in-amplifier...
Cisplatin (CDDP) is a highly active platinum-containing chemotherapeutic agent for use against solid tumors, including ovarian. However, like most antitumor agents, CDDP use is accompanied by non-tumor tissue toxicities leading to unwanted side effects, including neuropathy. To date, the mechanism(s) for these side effects are undefined. However, the clinical features...
Mt. Hood, in north-central Oregon, has experienced 13 M ≥ 3.0 earthquakes since 1980. 1812 earthquakes that range in magnitude from -1.1 to 4.5 have been recorded in the region during the same time frame. This paper analyzes four of the larger earthquakes to provide moment tensor solutions and relocated...
Previous studies have shown that both younger and older adults exhibit similar brain activity while anticipating monetary gain but older adults exhibit less brain activity comparing to younger adults while anticipating monetary loss. In Anderson et al.’s (2011) study, they found that visual search was slower with a salient, task-irrelevant...
The Speckled dace (Rhinichthys osculus) is the most widespread minnow in western North America (Gilbert and Williams, 2002). It has diversified widely across its range—both morphologically and genetically—and as such might rightly be called a species complex. Our ongoing work aims to determine where boundaries between potentially undescribed species lie...
For many years, scientists worldwide have been using glacial ice to reconstruct and study Earth’s past climates. While the most continuous records we have are from sites near both poles, there is also mid-latitude perennial ice in the form of mountain glaciers and cave ice. Very little is known about...
Studying the evolution of the Milky Way galaxy helps us understand our place in the Universe. Early evolution of the Galaxy can effectively be studied by observing stars with low metallicity values since they are the oldest stars still visible. Due to the formation of the Galaxy, the oldest stars...
Menu-Choice is a program that was developed to provide physical activity support and education to group homes that house adults with intellectual and developmental disabilities (I/DD). It has been shown that the physical activity levels for individuals living in group homes are low. This program was designed to provide direct...
"Red-sided garter snakes, Thamnophis sirtalis parietalis, from Manitoba, Canada are known to be hosts to trematodes, Alaria sp., in their population. Alaria sp. have been located in the tail tissue of the snakes. The non-reproductive stage of these obligate endoparasites, known as a mesocercaria, is trophically acquired by garter snakes....
The Jewett Mine is a hard rock mine located on the southern flank of Mount Baldy, approximately 1.6 km from Grants Pass in Josephine County, Oregon on the Grants Pass mining district. The Jewett Group contains 7 separate claims totaling approximately 1.42 km² and consists of several workings including an...
Red clover (Trifolium pratense) seed yields in Oregon are significantly reduced by the Clover Root Borer (CRB), Hylastinus obscurus. Since the CRB develops in clover roots and only emerges above ground briefly to mate and disperse, insecticides are ineffective for its control. In contrast, biological control may have potential as...
Our responses are faster when the response key location is compatible with target location than when it is incompatible, even when target location was irrelevant to the task (the Simon effect). This effect is observed even when two people shared the task (e.g., one pressing the left key and the...
As part of an HHMI funded research project, I showed that overexpression (OE) of actin (ACT2) in Arabidopsis thaliana alters the expression of genes involved in plant immunity. Others have previously shown that knockout (KO) mutants of actin depolymerizing factor 4 are affected in the same gene as ACT2-OE. For...
This project investigated transient photoconductivity in organic donor-acceptor (D-A) systems, where a flourinated anthradithiophene, ADT-TES-F, acts as the donor. Various acceptor molecules were used, with different sidegroups, and different HOMO (highest occupied molecular orbital) and LUMO (lowest unoccupied molecular orbital) energy level offsets relative to the acceptor. Thin film composites...
The purpose of this study was to compare the fine and gross motor skills of young children with and without autism. Within the Children and Youth with Disabilities Lab, the Movement Intervention for Young Children with Autism project seeks to create effective interventions to improve the fine and gross motor...
This work prepared YInMnO3, YCuTiO3, and YInFeO3 solid state pigments via microwave synthesis. The microwave-prepared pigments contain optical and structural properties similar to their furnace homologues. Overall synthesis times for each pigment have been significantly reduced via microwave synthesis, while keeping the same relative phase purity as solid-state.
The play "No Exit" was written by Jean Paul Sartre, adapted from the French by Paul Bowles and produced by special arrangement with Samuel French, Inc. This play was directed by Abbey Pasquini in the Oregon State University Lab Theatre From April 18th to the 21st. Copy of poster and...
Aim: There is growing interest in pharmacologic ascorbate (Asc) and its therapeutic properties (Levine et al. Adv Nutr 2011;2:78). W e examined cell viability, histone deacetylase (HDAC) expression, and related protein modifications in cancer versus non- cancer colon epithelial cells following exposure to Asc.
Methods: MTT assays were conducted in...
During mitosis, sister chromatids are separated by the action of the mitotic spindle. The mitotic spindle attaches to chromosomes at centromeres through a protein complex called the kinetochore. While ~100 proteins have been identified at kinetochores and centromeres, the function of most is poorly understood.
The centromere protein, CENP-T (Centromere...
The detection of mammalian FMO’s is important in the understanding of active FMO 2.1 and its role in metabolizing drugs to treat tuberculosis. Refinement of an absolute quantification (AQUA) mass spectrometry method is needed to be able to quantify the different FMO isoforms present in mammalian tissue. We are doing...
Metabolic disorders affect much of the population, and it is widely believed that they have a genetic basis as well as being influenced by dietary factors. Recent studies have revealed an important role for the neil1 gene in the prevention of metabolic diseases. NEIL1 is a DNA Glycosylase that catalyzes...
This project developed techniques and methods to measure single molecule conductance. Break gap junctions, used to measure electrical properties of single molecules, were explored. A Hewlett Packard mechanical nano-press was determined to be insufficient for creating a stable gap in which to conduct experiments. To avoid electromigration and bond annihilation...
Intensity beam profiles of a 633 nm laser off a super-polished glass surface were captured using surface polarization reflection. Profile capture can be difficult due to the relative intensities of molecular reflection versus macro reflection. Surface polarization reflection uses parallel polarized light incident at Brewster’s angle to extinguish macro reflection....
HafSOx is a dielectric material that also functions as an insulator. It is able to be
spin-coated onto a silicon substrate, creating a thin, amorphous film. It is very dense, which helps lead it to a high dielectric constant, making it ideal for electronic devices through the use of lithography....
Endogenous circadian clock regulation is essential to normal rhythmicity, particularly the timing of hormone release in the brain. In the context of mammalian reproduction, a surge of a specific hormone, gonadotrophin-releasing hormone (GnRH), initiates a surge of luteinizing hormone (LH) from the pituitary gland, which is required for ovulation in...
This project calculates the melting temperature as a function of pressure for a system defined by the Lennard-Jones 12-6 potential using molecular dynamic simulations. In a single atomistic simulation, the initial conditions are manipulated such that both a liquid and solid phase exist when thermal equilibrium is reached. Phase coexistence...
This item is a powerpoint presentation of an HHMI research project conducted during the summer of 2011 by Kyle Ireton, in partnership with Dr. Fredrick Stormshak. The objective of this study was to identify whether the myristoylated alanine-rich c kinase substrate (MARCKS) protein is phosphorylated in vivo, in response to...
Accurate diagnosis is the most important step in identifying and curing diseases. There are no accurate low cost disease diagnostic tools available for developing countries. The use of microfluidic paper-based analytical devices and colorimetric analysis of an assay response could solve these issues. Several colorimetric liver assays have been demonstrated...
Strong self-regulation in early childhood is a key predictor of academic and social success from elementary school through college (McClelland et al., 2012). This study analyzed the influence of the age of the child’s parent on the child’s self-regulation as measured by the HTKS (Head-Toes-Knees-Shoulders) measure. Relations between children’s self-regulation...
Pisaster ochraceus occurs in a variety of colors; the major hues being orange, brown, and purple. Harley et al. (2006) found that in areas on the open Pacific coast, where Mytilus californianus was present, less than 10% of the population of P. ochraceus were purple whereas in areas of the...
Between the years of 2006 and 2011, 183 marine mammal strandings were recorded and analyzed by the Veterinary Diagnostics Laboratory at Oregon State University. Most of the strandings were of pinnipeds and porpoises. The species represented were California sea lion (69 animals), Steller sea lion (18 animals), harbor seal (42...
Evidence-based interventions are considered to be the most successful interventions used in public health. They have the research to support their potential success when implemented by an organization. Evidence-based interventions are created and tested, then are implemented by a variety of organizations in various geographic locations, including non-profit organizations, public...
The purpose of this presentation is to show the source, methods, and results of creating a computerized display of the metabolic pathways of model plants Oryza sativa (rice) and Arabidopsis thaliana (thale cress) using the computer program PathVisio2. The finished products may be viewed and modified for free on www.wikipathways.org...
Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BP), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (aT) supplementation decreases BP-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that aT protection from BP exposure is gender-dependent, male and female rats received 7 daily subcutaneous...