Exercise increases B-vitamin (B6, B12, folate) dependent metabolic reactions, especially those related to energy production and the rebuilding and repairing of muscle tissue. These same B-vitamins are also important in maintaining low blood levels of homocysteine (Hcy), a cardiovascular disease (CVD) risk factor. Hcy levels rise when the metabolism of...
The aim of this study was to investigate the vitamin B-6 status of Saudi adult males and compare the status between rural and urban subjects. Fifty-one adult male subjects were recruited from urban (n=31) and rural (n=20) populations of Riyadh. These subjects were reclassified to cigarette smokers (n=19), water pipe...
Two studies were conducted to determine the effect of varying vitamin B-6 (B- 6) status on lymphocyte mitogenic response and pyridoxal 5'-phosphate (PLP) concentration in peripheral blood mononuclear cells (PBMC) in young women. In the first study, women were fed 1 mg/d for the first week and 1.5, 2.1 and...
The purpose of this study was to examine the effect of extreme exercise on vitamin B-6
metabolism and urea nitrogen. Nine men and five women completed two 5-day trials; Trial 1
(T1) included a 50-km ultramarathon on day 4 and during Trial 2 (T2) subjects were "inactive"
on day 4....
Previous studies have found that smoking may have a negative effect on
vitamin B-6 indices and have demonstrated a possible association between smoking
and depressed plasma pyridoxal-5'-phosphate (PLP) concentration. Individuals with
plasma PLP values below the adequate level of 30 nmoles/L might benefit from
consumption of vitamin B-6 supplements, but...
Four studies were conducted to evaluate the effect of varying levels of vitamin
B-6 (B6), protein and pyridoxine glucoside (PNG) on B6 status and requirements of
women. In the first two studies, women were fed a constant protein diet and vitamin
B-6 intakes of 0.84 to 2.39 mg/d during 10-...
In two studies we tested the effect of vitamin B-6
(B-6) intake on in vitro lymphocyte, proliferation and IL-2
production in healthy young women. In Study I, 6 women were
fed a constant diet containing 0.84 mg (4.96 μmols) of B-6
for 12 d, and 1.24 mg (7.33 μmols) and...
Trained male cyclists (6 in study 1, 5 in study 2) cycled to exhaustion (EXH) at
75% of VO₂ max twice; once in the non-supplemented (NS) state and once in the vitamin
B-6 (B-6)(20 mg PN) supplemented (S) state. The diet contained 2.3 mg B-6 in study 1
and 1.9...
Previous studies suggest that vitamin B-6 supplementation can alter fuel metabolism during
exercise and plasma amino acid levels at rest. To examine the effect of vitamin B-6
supplementation on plasma fuel substrates and amino acid levels during exercise, five trained
males (age: 29±7; V0₂ max: 54.7±6.2 ml/kg/min) performed two separate...