Index Catalog // ScholarsArchive@OSU

Composition of flavonoid phenolic polymers isolated from red wine during maceration and significance of flavan-3-ols in foods pertaining to biological activity

Creator:: Aron, Patricia M.
Abstract:: Representing the most common flavonoid consumed in the American diet, the flavanols and their polymeric condensation products, the proanthocyanidins, are regarded as functional ingredients in various beverages, whole and processed foods, herbal remedies and supplements. Their presence in food affects food quality parameters including astringency, bitterness, sourness, sweetness, salivary viscosity,...
Resource Type:: Masters Thesis
Full Text:: Effect on food quality............................................................................6

Investigations of gluten proteins from functional and historical perspective

Creator:: Zhang, Ying
Abstract:: Wheat (Triticum aestivum) is one of the world’s major staple food crops, with flour produced from starchy endosperm being used for breads, cakes, noodles and various other wheat-based foods. The unique bread making properties of wheat are primarily attributed to its gluten-forming storage proteins: gliadins and glutenins. This study investigated...
Resource Type:: Masters Thesis
Full Text:: )..………………………………………………64 3.2 Two-way ANOVA results of control effect…………………………………64 3.3 Onset temperatures under

Purification and characterization of recombinant calpain-5

Creator:: Wang, Mei-Chuan
Abstract:: Recombinant human calpain-5 was expressed in insect cells using a baculovirus system. The expressed calpain-5 was purified by both traditional chromatography and by affinity-column chromatography. Both methods yielded active protease. Calpain-5 displayed very limited hydrophobicity. This indicated that calpain-5 is not a membrane binding protein. Calpain-5 had pI of 8.3....
Resource Type:: Dissertation
Full Text:: cysteine proteases. Although the exact physiological roles of calpains remain to be elucidated, calpains

Estimation of the energy cost of walking 10,000 steps

Creator:: Birdsley, Kari L.
Abstract:: There is a strong campaign underway to promote increased physical activity among the U.S. population. The U.S. Surgeon General and the U.S. Dietary Guidelines have presented physical activity recommendations in terms of the amount of time accumulated in physical activity and/or in terms of energy expenditure over the course of...
Resource Type:: Masters Thesis
Full Text:: activity has a positive effect on one's physical well being. The American College of Sports Medicine

Exercise, nutrition, and homocysteine

Creator:: Joubert, Lanae Marie
Abstract:: Exercise increases B-vitamin (B6, B12, folate) dependent metabolic reactions, especially those related to energy production and the rebuilding and repairing of muscle tissue. These same B-vitamins are also important in maintaining low blood levels of homocysteine (Hcy), a cardiovascular disease (CVD) risk factor. Hcy levels rise when the metabolism of...
Resource Type:: Dissertation
Full Text:: exercise intensity is vigorous. Research examining the effect of exercise on Hcy is limited with no

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

Creator:: Farley, Sherry Mae
Abstract:: The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
Resource Type:: Dissertation
Full Text:: and d4-PK decreased in -T-injected rats demonstrating that vitamin E’s untoward effect on vitamin K

Impact of weak and strong acids on the destruction of lactic acid bacteria during high pressure processing

Creator:: Sarangapani, Rama Krishna
Abstract:: High hydrostatic pressure (HHP) affects the pH of weak acids due to an increased degree of acid dissociation while under pressure. The temporary pH reduction by high pressure in such a case may influence the barotolerance of microorganisms. The objective of this study was to determine the impact of weak...
Resource Type:: Masters Thesis
Full Text:: bacteria across a range of pH under high hydrostatic pressure conditions. The effect of two acid groups

The role of leptin in normal and pathological bone resorption

Creator:: Philbrick, Kenneth Alan
Abstract:: Particles generated from wear of prosthesis joint bearing surfaces induce inflammation and promote pathological periprosthetic osteoclast-mediated bone resorption (osteolysis). Obesity increases the risk of prosthesis failure. However, despite being morbidly obese, leptin-deficient ob/ob mice are resistant to osteolysis. These findings suggest that leptin exerts effects that act to increase particle-induced...
Resource Type:: Dissertation
Full Text:: .......................................................................................................................... 14 Study 2.2: Effect of housing temperature on particle-induced osteolysis in WT Study 2.3

Fibrinogen adsorption at heparinized silica interfaces : history dependence and protein concentration effects

Creator:: Joshi, Omkar
Abstract:: Adipic dihydrazide-modified heparin was prepared and subsequently immobilized on surface-activated silica wafers. X-ray photoelectron spectroscopy (XPS) was used to quantify the elemental composition of the silica surface at each stage of activation and results showed that successful immobilization had taken place. Contact angle measurements were made to verify the high...
Resource Type:: Masters Thesis
Full Text:: possible alternative is heparin immobilization on the biomaterial, so that the anticoagulant effect will

Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Creator:: Scheri, Richard C.
Abstract:: Chlordecone belongs to the class of persistent organochlorine pesticides that are remarkably resistant to environmental degradation. Even though their use was banned in the United States in 1978, these compounds can still be detected in both humans and wildlife throughout the world. Previous work has shown that the pretreatment of...
Resource Type:: Dissertation
Full Text:: promotes subcellular distribution of SR-BII to murine hepatic microsomes while having no effect on liver

Underlying Mechanisms of the Anti-inflammatory and Antioxidant Effects of Quercetin in Human Aortic Endothelial Cells : Implications for Vascular Inflammation and Atherosclerosis

Creator:: Li, Chuan
Abstract:: Atherosclerosis is the underlying cause of ischemic heart disease and stroke and is the leading cause of death worldwide, especially in developed countries. As an inflammatory disease of arteries in a hyperlipidemic milieu, expression of adhesion molecules, such as endothelial-leukocyte adhesion molecule-1 (E-selectin) and intercellular adhesion molecule-1 (ICAM-1), on endothelial...
Resource Type:: Dissertation
Full Text:: had no effect on Kelch-like ECH-associated protein 1 (Keap1) protein levels. In addition to

Metabolic effects of consumption of quercetin, ellagic acid, cherry, and apple phytochemical extracts in high-fat fed mice

Creator:: Smith, Sarah M.
Abstract:: Metabolic improvements and changes in gene expression were measured in mice fed polyphenol-rich extracts derived from apples and sweet cherries, and the common phytochemicals, quercetin and ellagic acid. Polyphenol-rich extracts were produced by solid phase extraction and column chromatography. Extracts and purified compounds were mixed into a high-fat (HF, 60%...
Resource Type:: Masters Thesis
Full Text:: line model will be used to measure physiological and molecular parameters. 1.1 Metabolic Disease

Evaluation of bamboo as livestock forage and applications of Yucca schidigera and Quillaja saponaria products in agriculture

Creator:: Greenway, Stephanie L.
Abstract:: Byproducts of bamboo processing, such as leaves and branches, may have potential as a livestock feedstuff. The objectives of this study were to evaluate seasonal changes in proximate composition of several bamboo species and reed canarygrass, and subsequently determine the digestibility of bamboo in ponies. Monthly samples of Phyllostachys bissetii,...
Resource Type:: Masters Thesis
Full Text:: physiological responses, and in fact may have an additive effect in combination, with saponins (Makkar and

Elevated ceramide levels contribute to the age-associated decline in vascular endothelial nitric oxide : pharmacologic administration of lipoic acid partially restores function

Creator:: Smith, Anthony R.
Abstract:: The vascular endothelium is a single cell layer that lines the lumen of the entire vasculature. It is the site of synthesis of nitric oxide (NO), a vasodilatory compound synthesized by endothelial nitric oxide synthase (eNOS). NO causes intracellular calcium sequestration of the vascular smooth muscle cells, relaxing and dilating...
Resource Type:: Dissertation
Full Text:: approximately 70 million by the year 2030 [192]. Thus, the physiological importance of the effect of age on the

Fibrinogen adsorption at heparinized silica interfaces : history dependence and adsorption time effects

Creator:: Lee, Hyo Jin
Abstract:: Heparin was modified with adipic diliydrazide and covalently linked to surface-activated silica. Contact angle measurements were made to determine changes in surface at various stages of the derivatization. Xray photoelectron spectroscopy was used to analyze the elemental composition of the surface at each step of immobilizing heparin as well and...
Resource Type:: Masters Thesis
Full Text:: effect of history dependence observed to be more pronounced on the heparinized silica. It is believed

Human platelet adhesion to heparinized silica surfaces

Creator:: Bolsinger, Travis Samuel Sebastian
Abstract:: Heparin was modified and immobilized to surface-activated silica surfaces using two different reaction schemes. End-aminated heparin was reacted with 2-iminothiolane to produce free thiol groups at the terminal ends of the heparin chains. The end-thiolated heparin was immobilized by reaction with a pyridyl disulfide activated poly[ethylene oxide]-poly[propylene oxide]-poly[ethylene oxide] triblock...
Resource Type:: Masters Thesis
Full Text:: repel proteins and have some sort of biological effect on the surface. 5 Li et al (1996

Age-related alterations in transcriptional regulation of hepatic glutathione synthesis : remediation by R-alpha-lipoic acid

Creator:: Shenvi, Swapna V.
Abstract:: Glutathione (GSH) is the predominant low molecular weight thiol antioxidant in liver tissue. GSH plays an important role in maintaining the intracellular thiol redox ratio as well as detoxification of electrophiles and xenobiotics. Aging leads to a significant decline (35%; P ≤ 0.05) in hepatocellular GSH levels. Using young (2-4...
Resource Type:: Dissertation
Full Text:: -factorial process characterized by a progressively reduced ability to cope with physiological challenges

In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

Creator:: Cardenas, Andres
Abstract:: Mercury and arsenic are known developmental toxicants and environmental exposures are ubiquitous worldwide from natural and anthropogenic sources. Prenatal exposure to both contaminants are independently associated with adverse perinatal health outcomes and latent disease risk that could be in part mediated by epigenetic reprogramming events. Fetal programming events involving DNA...
Resource Type:: Dissertation
Full Text:: effect of arsenic exposure mediated through DNA methylation in cord-blood. We observed that the inverse

Use of herbal feed additives in poultry feeding

Creator:: Nix, Kathryn
Abstract:: The use of an antibiotic as a growth promoter (AGP) began in the 1940’s with the discovery of growth responses from Streptomyces aureofaciens in the monogastric diet. However, resistance and residue problems have increased the negative consumer perception of growth promoting antibiotic use in animal diets. Although no direct link...
Resource Type:: Masters Thesis
Full Text:: lipids in laying hens. In experiment one, effect of the herbal blend (Superliv® Concentrate Premix

Molecular and cellular mechanisms of aromatic hydrocarbon axonopathy

Creator:: Kim, Min-Sun
Abstract:: Hydrocarbon solvents are widely used in the production of paints, adhesives, dyes, polymers, plastics, textiles, printing inks, agricultural products and pharmaceuticals. While the neuropathic potential of aliphatic solvents was shown in the 1970s, little is known about the neuropathic potential of aromatic solvents. The present study examines such solvents, 1,2-diethylbenzene...
Resource Type:: Dissertation
Full Text:: 3.1 In-vitro effect of diacetylbenzene isomers on test proteins bovine serum albumin and ribonuclease

Embryogenesis is dependent upon 12-lipoxygenase, 5-lipoxygenase, and alpha-tocopherol to modulate polyunsaturated fatty acid status and the production of oxidized fatty acids in zebrafish, Embryogenesis is dependent upon 12-lipoxygenase, 5-lipoxygenase, and α-tocopherol to modulate polyunsaturated fatty acid status and the production of oxidized fatty acids in zebrafish

Creator:: Lebold, Katherine M.
Abstract:: Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are polyunsaturated fatty acids required for proper embryonic development, specifically neurodevelopment. However, little is known regarding their conversion to other metabolites during embryogenesis. The oxidation of ARA gives rise to the biologically active eicosanoids and the oxidation of DHA gives rise to the...
Resource Type:: Masters Thesis
Full Text:: , COX-2 regulates ovulation and embryonic implantation87, however no effect of COX-2 knockdown was

Examining the Effects of High Vitamin E Diets on the Rodent Skeleton

Creator:: Kasper, Katherine G.
Abstract:: The primary goal of my study was to evaluate the effects of high dietary vitamin E on the rodent skeleton. The outcomes from my study assess the impact of high intakes of vitamin E and increased concentrations of its metabolite, carboxy ethyl hydroxy chromanol (CEHC), on bone turnover and skeletal...
Resource Type:: Masters Thesis
Full Text:: with low serum osteocalcin; however, the physiological significance of this relationship is unclear

Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cell

Creator:: Taur, Jan-Shiang
Abstract:: The goal of this dissertation is to investigate the interaction between cimetidine and dietary flavonoids using the Caco-2 cell transport model. It has been shown that flavonoids can change the bioavailability of pharmaceuticals, either by inhibiting metabolizing enzymes or inhibiting the drug efflux transporters. However, the effect of dietary flavonoids...
Resource Type:: Dissertation
Full Text:: inhibiting the drug efflux transporters. However, the effect of dietary flavonoids in the absorption of

Uncovering the mechanism of IL-4-mediated T cell survival

Creator:: Moscibrocki, Cathleen M.
Abstract:: Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
Resource Type:: Masters Thesis
Full Text:: , involving drastic biochemical, physiological, and morphological changes that lead to death. These events

Laboratory investigations of the natural fluorescence of marine phytoplankton

Creator:: Laney, Samuel R.
Abstract:: The influence of nitrate availability and irradiance on phytoplankton natural fluorescence was investigated in laboratory cultures of the marine diatom Thalassiosira weissflogii (Bacillariophyceae). Two cultures of phytoplankton, differing only in the nitrate-limited growth rate, were compared to learn how increases in irradiance influences natural fluorescence. Instrumentation was developed for these...
Resource Type:: Masters Thesis
Full Text:: > .......................................................... 58 3.5.3 Physiological Sources of Variability in Fnat ...................................... 61

Exposure of ionic hyper-regulated artemia to chlorine – 36 in a marine system

Creator:: Shaw, Christopher Glenn
Abstract:: Chlorine – 36 (36Cl) is produced naturally, through neutron activation of stable chlorine during nuclear weapons detonation, or from neutron capture on residual chlorine in graphite piles. It has a half-life of 301,000 years and decays by the means of beta decay with an average energy of 236.33 keV. Due...
Resource Type:: Masters Thesis
Full Text::  was developed  taking  into  account  a  cycling  effect  that  closely mimicked  the  research  data

The role of zinc in the molecular and cellular events in the prostate

Creator:: Yan, Michelle
Abstract:: Zinc is an essential mineral that is integral to many proteins and transcription factors that regulate key cellular functions. The normal prostate accumulates high concentrations of zinc; however, malignant tissues have significantly lower zinc levels. This unique relationship between zinc and the prostate has sparked interest in the role of...
Resource Type:: Dissertation
Full Text:: expression of zinc transporters may explain this effect, as expression of zip1 and zip3 were significantly

Dose response of zebrafish exposed to gamma radiation

Creator:: Haskins, Hillary Kate Marlane
Abstract:: Space radiation biology is an emerging field of research with a focus on improving the health and safety of astronauts in low-Earth orbit (LEO) and deep-space missions. Eye health is especially important to astronaut functionality. Recent studies have found an increased risk of cataract formation in astronauts with higher lens...
Resource Type:: Masters Thesis
Full Text:: damage. Cataract formation is a well-known effect of ionizing radiation exposure. It was once

The Roles of Dietary Nitrate in Bone and the Gut in an Ovarian Hormone-deficient Rodent Model

Creator:: Conley, Melissa N.
Abstract:: Osteoporosis is a common metabolic bone disease, affecting a third of women and a fifth of men over age 65. In the US, annual health care costs associated with osteoporosis are estimated to be over $20 billion. Osteoporosis is associated with increased fracture risk, which has been demonstrated to predict...
Resource Type:: Dissertation
Full Text:: turnover. Further, dietary nitrate had no beneficial effect on mineral apposition rate, bone formation

Studies on effect of stabilizers, chelators and inherent periodicity on nanoparticle antioxidant activity

Creator:: Zhou, Zheng
Abstract:: The level of reactive oxygen species (ROS) is tightly regulated in biological systems as overproduction can lead to oxidative stress and result in a number of diseases. Due to its negative effects, antioxidants are studied and used against ROS in medicine, pharmaceuticals and therapeutics. Because of issues with the uptake...
Resource Type:: Masters Thesis
Full Text:: Studies on Effect of Stabilizers, Chelators and

Physiological, proteomic, and whole-genome transcriptional responses of Nitrosomonas europaea to heavy metals (Zn²⁺,Cd²⁺, Cu²⁺, and Hg²⁺) and cyanide : identification of heavy metals and cyanide stress response genes

Creator:: Park, Sunhwa
Abstract:: Nitrosomonas europaea (ATCC19718) participates in the biological removal of nitrogen from wastewater by oxidizing ammonia to nitrite, the first step in nitrification. This bacterium is sensitive to heavy metals (Zn²⁺, Cd²⁺, Cu²⁺, and Hg²⁺) and cyanide, compounds commonly encountered in wastewater treatment plants. Therefore, we characterized physiological and transcriptional responses...
Resource Type:: Dissertation
Full Text:: . Title: Physiological, Proteomic, and Whole-Genome Transcriptional Responses of Nitrosomonas europaea

Molecular characterization of bacterial populations implicated inthe anaerobic metabolism of toxic plant alkaloids from two different experimental and environmental sources

Creator:: Rattray, Rogan MacKay
Abstract:: There have been many studies that describe the protective degradation or metabolism of potentially harmful plant toxins, such as, mimosine from Leucaena leuconcephala, pyrrolizidine alkaloids from tansy ragwort (Senecio jacobaea), oxalate and some mycotoxins by rumen microbes. There are many cases of plant-related toxicoses suffered by ruminant animals where there...
Resource Type:: Masters Thesis
Full Text:: cause of toxicosis. The physiological activities of ergovaline and the other ergot alkaloids have been

Sesame oil increases plasma γ-tocopherol and inhibits γ-tocopherol metabolism in humans

Creator:: Lee, Sangeun
Abstract:: In rats, sesame lignans increase plasma γ-tocopherol concentrations and inhibit γ-tocopherol degradation to its metabolite γ-carboxyethylhydroxychroman (γ-CEHC). To test if sesame lignan consumption inhibits γ- tocopherol metabolism in humans, muffins prepared with either corn oil (control) or sesame oil and an equimolar mixture of deuterium labeled d6-α- and d2-γ- tocopheryl...
Resource Type:: Masters Thesis
Full Text:: ................................................................................. 7 γ-Tocopherol’s physiologic effect on human health

Exploring the cellular mechanisms of Cnidarian bleaching in the sea anemone Aiptasia pallida

Creator:: Perez, Santiago
Abstract:: Many members of the Phylum Cnidaria are mutualistic with unicellular dinoflagellates belonging to the genus Symbiodinium. Corals are the most widely recognized example of these associations due to their key ecological importance in coral reef ecosystems where they serve as the structural and trophic foundation of these rich ecosystems. Coral...
Resource Type:: Dissertation
Full Text:: know how the differential physiological susceptibility of the algae translates mechanistically into

Effects of Elevated CO₂ on Speckled Sanddab (Citharichthys stigmaeus) Behavior

Creator:: Andrade, Jessica F.
Abstract:: The direct and indirect effects of ocean acidification (OA) are a growing concern, particularly in areas already experiencing elevated levels of oceanic CO₂. Studies with marine fishes suggest that elevated CO₂ levels may affect behavior by interfering with an important brain neurotransmitter. Studies examining the effects of OA fish behavior...
Resource Type:: Masters Thesis
Full Text:: occur over the next 150 years (~1,000 μatm and ~1,600 μatm). While there was no major effect

Chronobiology of garter snakes : environmental and hormonal mechanisms mediating hibernation and reproduction

Creator:: Lutterschmidt, Deborah I.
Abstract:: Most vertebrates exhibit seasonality in many life history traits. Such seasonal rhythms are temporally organized via the transduction of environmental cues (e.g., photoperiod, temperature) into appropriate endocrine signals. However, among ectothermic vertebrates that undergo continuous winter dormancy, temperature is the only environmental cue available for synchronizing seasonal rhythms. Most intriguing...
Resource Type:: Dissertation
Full Text:: ). ...........................................................................................138 4.2 Effect of capture stress on (A) corticosterone and (B) melatonin concentrations of

Effects of Intranasal Oxytocin on Attachment in Pet Dogs (Canis lupus familiaris)

Creator:: Thielke, Lauren E.
Abstract:: The present study explored the effects of intranasal oxytocin (OT), a naturally occurring hormone, on the behavior of pet dogs in an attachment test. Each dog participated in two testing sessions. On one visit saline was administered nasally and on another OT was administered nasally. Condition order was counterbalanced. Following...
Resource Type:: Masters Thesis
Full Text:: , this effect was not observed. In fact, in the baseline phase, dogs spent significantly more time

Central and Peripheral Nervous System Underpinnings of Moral Elevation

Creator:: Piper, Walter T.
Abstract:: The present study characterized physiological responsivity during moral elevation, or elevation, a prosocial emotional state triggered by witnessing displays of altruism and moral beauty. Participants watched video stimuli that induced elevation, or amusement as a control condition, while heart rate (HR), respiratory sinus arrhythmia (RSA), skin conductance responses (SCR), and...
Resource Type:: Masters Thesis
Full Text:: R. Saturn The present study characterized physiological responsivity during moral elevation, or

Metabolic effects in C57BL/6J mice fed a high-fat diet supplemented with Pinot noir juice and wine extract or quercetin, ellagic acid and resveratrol

Creator:: Zhao, Bingxin
Abstract:: Moderate wine consumption, particularly pigment-rich red wine, is thought by many to be beneficial for the cardiovascular system. Both ethanol and phytochemicals are thought to contribute to this cardioprotective property. Metabolic disturbances associated with overconsumption of food are related to the initiation and progression of many chronic diseases, and cardiovascular...
Resource Type:: Masters Thesis
Full Text:: antagonistic effect of extract components in specific metabolic activities. In the future, mechanistically

Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model

Creator:: Gaddini, Gino W.
Abstract:: Background: Alcohol is a nonessential nutrient widely consumed throughout the world. Chronic alcohol abuse is associated with numerous adverse skeletal effects. However, prior to this study, the effects of alcohol abuse on intracortical bone remodeling in an animal model had not been investigated. Reduced intracortical bone remodeling could impair repair...
Resource Type:: Masters Thesis
Full Text:: [86], others reporting higher resorption [87, 90, 92, 94], and some reporting no effect [76

Fluoride content of foods made with mechanically separated chicken as a potential risk factor for dental fluorosis in infants and children

Creator:: Fein, Noelle J.
Abstract:: Although fluoride is an important trace element in the prevention of dental caries, it has a narrow range between beneficial and toxic effects. Excessive fluoride intake for example can cause dental fluorosis in infants and children whose teeth are still developing. The primary source of this unwanted fluoride has been...
Resource Type:: Masters Thesis
Full Text:: needed to achieve a desired effect. Therefore, it is important to be aware of sources of fluoride that

Effects of alfalfa on uterine growth of ovariectomized prepubertal ewe lambs

Creator:: Sexson, Clinton
Abstract:: Alfalfa accumulates phytoestrogens and when ingested binds the estrogen receptor and induces morphological changes similar to endogenous estrogens. The objective of this study is to evaluate morphological changes in uteri, vulva, and teats of ovariectomized prepubertal ewe lambs. Eighteen prepubertal ewe lambs were ovariectomized in November 2000 and fed nonestrogenic...
Resource Type:: Masters Thesis
Full Text:: . Observer effect on mean teat score for all treated ewes on all days of observation

Chronic exposure of rodents to indole-3-carbinol and 3,3'-diindolylmethane : implications for drug metabolism, chemoprevention and human health

Creator:: Leibelt, Dustin A.
Abstract:: Indole-3-carbinol (I3C) is a naturally occurring plant alkaloid, found in significant concentrations in cruciferous vegetables such as broccoli and Brussels sprouts. I3C is an unstable compound that undergoes rapid oligomerization in an acidic environment to form higher order condensation products (I3C-ACPs), such as 3-3'-diindolylmethane (DIM). Both I3C and DIM are...
Resource Type:: Dissertation
Full Text:: DIM exposures in rodent models to further elucidate the effect these compounds might have on health

Analysis of the effect of the potassium ion on fowl sperm motility

Creator:: Gamble, Kari
Abstract:: Fowl sperm are believed to be immotile prior to ejaculation. The concentration of potassium found in deferent duct fluid is approximately 8 times higher than that found in blood plasma, which is 5 mM in Gallus domesticus. The effect of ionic potassium on fowl sperm motion was tested in a...
Resource Type:: Masters Thesis
Full Text:: Master of Science in Animal Sciences presented June 14, 2004. Analysis of the Effect of the Potassium Ion

Effects of whole body vibration and progressive resistance exercise on balance and lower extremity strength

Creator:: Dodge, Nathan
Abstract:: Whole body vibration (WBV) is widely used as a mechanical stimulus for neuromuscular training, and to a lesser extent, in the treatment of patients undergoing physical rehabilitation. PURPOSE: To quantify any beneficial and/or synergistic effects associated with the longitudinal administration of WBV and progressive resistance (PRE) exercise on lower extremity...
Resource Type:: Masters Thesis
Full Text:: ...................................................................................... 47 3.1. Categories of Effect Size, as proposed by Cohen

Physiological response of Nitrosomonas europaea to oxytetracycline, chromium, and silver

Creator:: Schaerer, Morgan A.
Abstract:: Nitrosomonas europaea carries out the first step in the biological nitrogen removal process in wastewater treatment by oxidizing ammonia to nitrite. It has been shown to be sensitive to a wide range of contaminants. The antibiotic oxytetracycline and the heavy metals chromium and silver have been found in wastewater influent....
Resource Type:: Masters Thesis
Full Text:: 21, 2009. Title: Physiological Response of Nitrosomonas europaea to Oxytetracycline, Chromium

An allometric examination of the relationship between radiosensitivity and mass

Creator:: Bytwerk, David Paul
Abstract:: The results of a review of six decades of existing literature for 50% lethal dose data across a range of phyla are presented. The collected 50% lethal dose data is limited to adult organisms subjected to acute doses of gamma radiation. The data collected is examined to determine whether useful...
Resource Type:: Masters Thesis
Full Text:: . Rules and regulations dealt exclusively with the effect of radiation on h. sapiens, reasoning that

Control of p53 tumor suppressor and peroxiredoxin activity through shifts incellular redox balance

Creator:: Stoner, Christopher S.
Abstract:: Aerobic organisms have evolved many sensory mechanisms that allow response to oxidants in the environment. One area of interest is the relationship between the activity of the tumor suppressor protein p53 and the redox state of thioredoxin. Human p53 activity is severely compromised in budding yeast lacking thioredoxin reductase. Evidence...
Resource Type:: Dissertation
Full Text:: , and the effect on p53 activity in wild- type and thioredoxin reductase-null yeast was determined

Chlordecone (CD), a mixed steroid X receptor (SXR) and estrogen receptor alpha(ERα) agonist, altered hepatic cholesterol (CH) homeostasis and lipoprotein metabolism

Creator:: Lee, Junga
Abstract:: Overtly non-toxic doses of organochlorine (OC) insecticides perturb lipid homeostasis in mice and rats. To increase understanding of how chlordecone (CD), an OC insecticide, modulates cholesterol (CH) homeostasis, we determined the effect of CD pretreatment on the tissue and hepatic subcellular distribution of exogenous [¹⁴C]CH. Corn oil alone or CD...
Resource Type:: Dissertation
Full Text:: ) homeostasis, we determined the effect of CD pretreatment on the tissue and hepatic subcellular distribution

The use of natural plant extracts as a feed additive to prevent laminitis in lactating dairy cows

Creator:: Pierson, Miranda L.
Abstract:: Two experiments were conducted looking at both acute and sub-acute laminitis. An acute nutritional induction model was used to examine whether blood profiles and gene expression are similar to other studies conducted using an endotoxin induction model. Twelve sheep were randomly assigned to three treatment groups which were control, 4-hour...
Resource Type:: Masters Thesis
Full Text:: physiological responses similar to lipopolysaccharides (LPS) (Mullenax et al., 1966). It was hypothesized

Search Constraints

Search Results

Limit your search