One group of four adult White Leghorn male chickens was fed a
diet containing 7.3% linoleic acid and 32.4 mg/ kg of added vitamin E
(group IV) for 50 weeks which was designated as the positive control.
A second lot (group I) containing 14 males received the same level of...
An in vitro study was conducted to investigate the metabolism and distribution of Se⁷⁵-selenite and Se⁷⁵-selenomethionine (SEM) in
chick blood. Se⁷⁵-selenite is taken up by RBC (13% within 20
minutes) and expelled into the plasma to become bound to proteins. In
contrast, Se⁷⁵-SEM showed a more gradual and continuous buildup...
The relative enrichment of skin sebaceous gland lipids with deuterium-labeled α-tocopherol was compared with plasma enrichment to evaluate the delivery of vitamin E to skin. For the first week of this study, each subject consumed a daily dose of deuterated vitamin E (150 mg of an equimolar mixture of RRR-α-[5-(C²H₃)]-(d₃)...
Vitamin E was first described in 1922 as an unknown factor required for impregnated rats to carry their offspring to term. In fact, when vitamin E was chemically characterized it was given the name "tocopherol" derived from the Greek: tokos = childbirth; phero = to bear; and –ol, indicating an...
The objective of our study was to investigate the effect of selenium on
selenoprotein W. Western blot analysis indicated that selenoprotein W is present in
muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W
was not altered in rats fed various selenium levels. Among muscle, brain,...
Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...