Aquifer recharge is generally driven by fluids that move from the Earth’s surface to groundwater through the unsaturated zone, also known as the vadose zone. When the vadose zone is fractured, fluids, which may include contaminants, can move through the fracture network as well as the porous matrix. Such a...
Maintaining genome integrity is essential for an organism, as mutation
accumulation can lead to cancer, reduced fitness, and heritable diseases in offspring.
Therefore the study of mutations, how they are induced, and how they are prevented is
vital. Biomonitor systems are useful for understanding the relevant biological effects
of a...
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John B. Hays
Maintaining genome integrity is essential for an organism, as mutation
Genomic instability underlies diseases of unregulated cell growth that result in
cancers and developmental abnormalities in humans. Similar genome destabilizing
mechanisms are used to create genetic variety in crops for use in breeding and trait
development. Errors that occur during DNA replication may cause mutations if
they are not corrected...
Four-stranded DNA junctions (also known as Holliday junctions) are structural intermediates involved in a growing number of biological processes including DNA repair, genetic recombination, and viral integration. Although previous studies have focused on understanding the conformational variability and sequence-dependent formation of Holliday junctions in solution there have been relatively few...
NCRP report No.160 states that medical exposure increased to nearly half of the total radiation exposure of the U.S. population from all sources in 2006 (NCRP 2009). Part of this increase in exposure is due to the rise in nuclear medicine procedures. With this observed growth in medical radionuclide usage,...
The DNA mismatch repair (MMR) pathway maintains genomic stability and
reduces cancer risk (colorectal and other internal cancers) by correcting polymerase
errors and activating cell cycle checkpoints and apoptosis in response to DNA damage.
Few studies have examined the influence of commonly encountered environmental
mutagens/carcinogens on the etiology of MMR-deficient...
The multistage model of carcinogenesis states that an accumulation of mutations in genes that are important for maintaining cellular homeostasis may lead to cancer. A specific type of mutation observed in particular types of cancer is the CC-->TT mutation found in the TP53 gene of patients with basal or squamous...
The aim of this study was to gain more information about the
interactions between DNA and the histone octamer during the
process of transcription. This work used a pUC8 plasmid derivative
that contained the core promoter region of the RNA polymerase I of
Acanthamoeba castellanii, placed upstream of four repeats...
A crucial factor in determining the accuracy of DNA replication is
maintenance of a balanced supply of deoxyribonucleoside triphosphates
(dNTPs) at replication forks. Perturbation of dNTP biosynthesis can
induce dNTP pool imbalance with deleterious genetic consequences,
including increased mutagenesis, recombination, chromosomal
abnormalities and cell death. Using the T4 bacteriophage system,...
In recent years Zaire has changed from a net exporter to a
net importer of maize. Four districts of South Central Zaire were
selected to investigate factors which limit the production and the
supply of marketed maize grain in Zaire.
Farmers in this area were interviewed to collect data on...
The mycosporins, formerly called P310's are secondary metabolites
of fungi closely associated with fungal reproductive processes that
require light. The structurally related iminomycosporins are found in
marine plants and animals and may also have functions related to
light. In this study, approaches toward the asymmetric synthesis of
the mycosporins are...
This dissertation describes how to apply pharmacokinetic simulations and modeling in a clinical setting to monitor and adjust drug dosing in special patient populations. Pharmacokinetic simulations were used to investigate efficacy and risk of drug toxicity of a new dosing regimen for aminoglycoside antibiotics when administered to renal failure patients....
Water temperature influenced interactions between redside
shiners and juvenile steelhead trout (≥1+) in the field and the
laboratory. Distribution of the two species within various habitats
was determined in three streams with different water temperature
regimes. The range of habitats occupied by trout in allopatry at
cool temperatures and at...
The purposes of this study were to determine which research tasks
were necessary to the job descriptions of public school
administrators, secondary and elementary teachers; what task clusters
could be identified for college and university curriculums; what
differences existed between sample groups.
The instrument was validated through the Delphi technique....
To identify factors limiting 'Candidatus Pelagibacter ubique' maximum cell density and growth rate in pure culture on seawater, the genome sequence of 'Cand. P. ubique' was analyzed, culturing experiments with organic and inorganic nutrient additions were made, and radiotracer uptake experiments were performed. The genome was sequenced, custom data mining...
Nutrient losses of the biologically responsive anions, nitrate and bicarbonate together with the major cations, were monitored on 14 small watersheds in Oregon's Coast Range and evaluated in relation to management-induced disturbance. Mixed forests of Douglas-fir and red alder had dominated these high-nitrogen sites prior to treatment. A paired-watershed experimental...
This thesis describes a study of the synthesis, stereochemistry,
and reactivity of cobalt(III) cysteinato (CyS) and related thiolato complexes.
The preparation of [Co(en)₂CyS]⁺ resulted in a product solution
containing a mixture of diastereomers in the ratio 2.3:1 (Δ:A). The isomers were separated by ion exchange chromatography, and
their absolute configurations...
The first part of this thesis describes a study of the
characteristics of oxidation of a 1:2 iron(III):thiolate system in
methanolic solution and in water. This system was investigated as a
potential analog for the cysteine- and cysteamine-dioxygenase catalyzed
0₂-oxidation of cysteine and cysteamine, respectively, to the
corresponding sulfinic acids....
Part I describes the synthesis of bis(fac-S)((tris)2-aminoethanethiolatoiron( III))iron(III) chloride. The compound was first discovered during an attempt to prepare a ternary complex of iron, thiolate and pi-acid ligand. The compound is a reasonably air-stable iron(III)-thiolate that contains a linear tri-iron cluster with each iron bridged to the adjacent iron by...
Large amounts of plant tissue are used in the production of many
canned, frozen and dried foods. Some of this material is unsatisfactory
in appearance and texture, despite careful processing from high quality
raw materials.
In the present study, the changes induced in soft fruits by controlled
heating and freezing...
This thesis work researches the theory and application
of systems performing omnidirectional, non-direct
path optical data communication (ONP systems). Such
systems are characterized by 1) the communication involves
a local, usually circular area; 2) Obstacles are allowed
between a transmitter and the receivers. This is in
contrast to the point-to-point...
The suitability of discrete least-squares optimal (Wiener) filters
for deconvolution of tone-burst waveforms is studied. It is shown
that: (1) such waveforms are not well suited to these filters without
preprocessing, (2) the use of exponential weighting results in a significant
improvement in filter performance and (3) that "phase-unwrapping"
in...
Hybrid-Meshnet is a communication subnet architecture for local area networks (LANs) designed to achieve a high degree of network performance and flexibility. These objectives are achieved by utilizing a dual channel structure. A token ring is used for short or prioritized data transmissions. A complimentary mesh network with arbitrary data...
Enzymic systems able to hydrolyze the compounds forming
the supporting structure of plant tissues have a major effect upon
the texture of fruit products.
The objective of this thesis was the development of a theory
to explain the textural changes in fresh and processed strawberries.
The presence of pectinolytic enzymes...
FISHNET (Facilities Integrated in a Shared Habitat) is a communication subnet architecture utilizing a hybrid application of point-topoint and broadcast communications to achieve a high degree of network performance. This objective is achieved through utilizing a dual bus structure: a data bus and a control bus. The data bus consists...
Two new medium access protocols for ring type local area networks,
CTR (Concurrent Token Ring) protocol and DRUID (Destination Removal
withoUt Intermediate node Delay) ring protocol, are proposed, designed and
analyzed. A destination partial removal technique is designed and used in
these two protocols to support concurrent message transmission and...
As a result of the automation revolution, robots
are assuming ever more complex and demanding tasks.
Robot system control schemes for fast and precise robot
motion require utilization of the entirety of the robot
dynamic formulations and the ability to evaluate these
formulations in real-time. The dynamic formulations,
which take...
Local computer networks are being installed in diverse application areas. Many of the networks employ a distributed control scheme, which has advantages in performance and reliability over a centralized one. However, distribution of control increases the difficulty in locating faulty hardware elements. Consequently, advantages may not be fully realized unless...
Control algorithms for accurate and fast moving robots require the use of the complete dynamic model of the robot. The complete dynamic model takes into account the nonlinearity and coupling terms of the whole structure. The time of computing the dynamic equations determines whether they are usable in practical applications....
The variable length, six-electrode plasma source for atomic
emission spectroscopy described here is operated from three
compact, simple, and inexpensive direct current power supplies. The
vertical arcs formed between the three electrode pairs completely
entrain the sample and are typically operated at 40 V and 20 A.
Three concentric quartz...
The purpose of this study was to determine the extent to which
the philosophy, administration and implementation of public recreation
and leisure service has contributed to the democratization of black
Americans for the period 1906-1972. The study attempted to describe
the interplay and connection between the black, subordinated community
and...
A complex and sometimes serious problem facing modern day forest
managers is that of estimating and analyzing potential on-site impacts
which result from forest activities. A major type of adverse impact
is man-Initiated forest erosion. This consequence can be substantially
magnified when forest harvest and road activities are implemented in...
A new method for determining ion exchange equilibrium
data by liquid scintillation counting of the equilibrated solution
phase is described. This method has been applied to determine
equilibria between Dowex 50W X8, a commercial strong cation exchange
resin, and binary and ternary solution containing the varying combinations
of H⁺¹, Cs⁺¹,...
Nine feeding trials and four laboratory scale experiments were conducted in this study. The study consisted of: (1) use of grass straw:corn juice (CJ) silages with fishmeal and/or alfalfa hay supplementation in beef heifers, sheep, pregnant dairy heifers, water buffaloes and Hereford cows; (2) use of cull onions:grass straw silages...
In wireless sensor network applications, low-power operation of the wireless receiver is critical. To address this need an ultra-low power Binary Frequency Shift Keying (BFSK) receiver using the super-regenerative architecture is developed.
A prototype receiver is built and tested for operation in the 900 MHz ISM band. Lab measurements show...
Tomato [Lycopersicon esculentum Mill.] plants are chilling sensitive and do not
naturally accumulate glycinebetaine (GB), a metabolite that functions as a stress
protectant in plants. While GB can increase tolerance of tomato plants to salt and
drought stresses, its effect on chilling tolerance has not been examined. To evaluate
whether...
An automated multielement flame atomic fluorescence (AF) spectrometer based on microcomputer control was constructed to determine four elements simultaneously. The instrument employs a multiple exit slit monochromator where the light from various exit slits is directed to a single detector with a mirrored funnel. Each element is excited to fluoresce...
The aim of this investigation was to develop an Adjustment Assessment Instrument for Omani College Students. The adjustment instrument items were constructed and grouped into academic, family, social and personal adjustment areas common to Omani college students. The content validity of the adjustment instrument was determined by utilizing two Delphi...
A multispectral retrieval method is developed on the 100 km regional scale to extract
the temperature, particle size, fractional cover and 11-μm emissivity of clouds which
may be semitransparent in the infrared based on emitted radiances. The scheme utilizes
the nonlinear relationship between emitted radiances when clouds are semitransparent and...
Black Butte presents a unique natural laboratory for ecological
study. It is a volcanic cone of uniform configuration located in the
rain shadow on the east flank of the Oregon Cascades. Soils are of
very recent origin with no obvious development of horizons.
Physical and chemical analysis revealed little dissimilarity...
The purpose of the study was to investigate the effect of trials-to-criterion on the retention of a discrete motor skill (overhand beanbag throw) by moderately mentally retarded and severely mentally retarded individuals. Nonmentally retarded individuals were involved as a control group. The subjects were grouped by degree of retardation and...
In this dissertation, a series of studies in the field of terahertz (THz) science are presented, specifically using nonlinear THz spectroscopy. We exploit huge field enhancement and subwavelength confinement in plasmonic structures. There are three distinct projects which will be discussed: nonlinear THz spectroscopy using plasmonic induced transparency (PIT), THz-triggered...
Recently, high carbohydrate diets were recommended for the
treatment of diabetes mellitus. All aspects of these diets, however,
have not been fully tested — particularly in insulin dependent
diabetes mellitus (IDDM). The present study was designed to
investigate the effects of high carbohydrate, low fat diets (HCLFD)
on blood glucose...
This dissertation describes formulation of a gastric retention device (GRD) and sustained release (SR) hydrochlorothiazide beads at Oregon State University. Formulation condition and amounts of excipients had significant influence on characteristic of the GRD. The GRD containing SR hydrochlorothiazide beads was employed to assess bioavailability/bioequivalency study in healthy subjects. An...
Cores taken from the ridge areas of the Gorda-Juan de Fuca
plate have a sedimentation rate that is appropriate for the study of
late Quaternary stratigraphy. An analysis of the clay and silt
mineralogy of the cores using X-ray diffraction methods and by
noting changes in the foraminiferan-radiolarian abundances in...
Metabolic and performance parameters of beef calves were
compared between Se supplemented (Se) and control (C) dam
treatment groups from known Se deficient cattle. Four
trials were conducted at three locations involving 50,
36, 25 and 39 experimental dam/calf pairs. Se
supplementation was either two 30 gram oral boluses (90%...
Streptococcus lactis C2F and Streptococcus cremoris 459 grew
to a maximum population of 1 to 2 x 10⁹ colony forming units (cfu)/ml with a generation time of 96 min in 11% nonfat dry milk (NFDM)
under static conditions at 22° C.
Streptococcus diacetilactis 18-16
grew to a maximum population of...
A series of 8 experiments was conducted to investigate various
methods of delaying the sexual maturity of developing White Leghorn
(W. L.) pullets grown during a period of increasing day length and to
control the feed intake of W. L. layers. In the first five experiments
W. L. pullets were...
Five lithologic units, ranging in age from Middle Miocene to Recent,
are defined on the basis of continuous seismic reflection profile records.
Two of the units are Miocene sedimentary and volcanic rocks that have been
truncated to form a major unconformity (post-orogenic surface) related to
the most recent major tectonism...
The focus of this study was to determine if S₁ family recurrent
selection might be successfully used for barley improvement.
Objectives were: 1) to identify suitable methods of evaluating grain
yield in small plots, 2) to study the effects of intermating on mean
values and variances of selected agronomic characters,...
New ice cores retrieved from the Taylor Glacier (Antarctica) blue ice area contain ice and air spanning the Marine Isotope Stage (MIS) 5/4 transition, a period of global cooling and ice sheet expansion. Chronologies were determined for the ice and air bubbles in the new ice cores by visually matching...
Cellooligosaccharides are the reaction intermediates produced during the hydrolysis of cellulose to glucose. Hence, they have the same chemical structure as cellulose, just shorter chain lengths. Cellooligosaccharides up to DP eight are soluble in water. The soluble cellooligosaccharides can be used "as is" in the food industry as non-digestible oligosaccharides...
Eukaryotic small RNA (~20-30 nucleotides) are diverse regulatory molecules that repress gene expression at the transcriptional and post-transcriptional levels, defend hosts against invading viruses and defend genomes against selfish DNA elements. Small RNA populations are studied by high-throughput sequencing of the total small RNA fraction isolated from cells, however, the...
In an effort to describe the plant communities and
succession of the Oregon coastal grasslands, vegetation
and environmental data were collected from 75 stands at
24 separate locations ranging from Cape Falcon in Tillamook
County to Cape Ferrelo in Curry County. The vegetation
data consisted of cover and frequency values...
A method is described for the determination of N-nitrosoproline
(NOPRO) in cured meat products. NOPRO was extracted with ethyl
acetate from a slurry of cured meat and water after the addition of
ammonium sulfamate and acid. This nitrosamino acid was converted
to the methyl ester and after further purification, it...
Spirituality is an important component in the lives of many Black Americans. Black American life has spirituality woven into multiple aspects. From what clothes to wear, what words to use when creating a dialogue with others, which television shows to watch, which jobs to pursue, how to treat those who...
Chinook salmon, Oncorhynchus tshawytscha, returning to the Yukon River basin and other large river systems in western Alaska have declined dramatically since the late 1990s. This continuing trend has raised concerns over the future status of the returns, and severely impacted commercial and subsistence fisheries within the drainage. Management is...
Analogous to ocean surface waves, waves in the ocean interior also experience steepening, breaking, and dissipation as they approach the coastline. Much less is known about this internal beach. In this work, extensive moored Acoustic Doppler Current Profiler and temperature/salinity data together with optical remote sensing are combined to describe...
Perennial ryegrass (Lolium perenne) - white clover
(Trifolium repens) hill-land pastures were grazed at
different times in the winter to study the effect of time
of winter grazing on plant response and forage production.
The same pastures were grazed by sheep once in early
December, January, February, March, or April...
Sorbitol-induced osmotic stress (SIOS) to the root was found to be effective in
reducing transpirational water loss in plants during water stress. Mechanisms of SIOS in
stomatal control were investigated in containerized apples (Malus domestica Borkh.
'Gala'/M26) when leaf water potential (Ψw), osmotic potential (Ψs), turgor potential (Ψp),
stomatal conductance...
The primary purpose of this study was to determine which factors related to adult 4-H volunteer empowerment in 4-H youth development settings. This study examined the relationship of adult 4-H volunteers’ perceived leadership styles of Oregon 4-H Youth Development Educators (YDE) to the adult 4-H volunteer sense of empowerment. In...
The teliospore of Tilletia caries germinates to produce a promycelium
with a whorl of primary sporidia at its tip. The time between
emergence of the promycelium and the development of primary sporidia
averaged 2.3 h. Fusion between compatible sporidia occurred within
an additional 3.8 h. Primary sporidia appeared to be...
Fifty species and subspecies and six varieties in eight genera of
the family Tabanidae are recognized from Oregon. The following genera
are represented in Oregon: Apatolestes Williston, Pilimas Brennan,
Stonemyia Brennan, Silvius Meigen, Chrysops Meigen, Atylotus Osten
Sacken, Hybomitra Enderlein and Tabanus Linnaeus. Adults and larvae
were collected from various...
We consider the parallelization of Monte Carlo algorithms for analyzing numerical models of charge transport used in semiconductor device physics. Parallel algorithms for the standard k-space Monte Carlo simulation of a three band model of bulk GaAs on hypercube multicomputers are first presented. This Monte Carlo model includes scattering due...
Clean technologies can address multiple challenges associated with climate change, environmental protection, and human health. However, the impact desired by introduction of such technologies is achievable only if new options effectively replace inefficient, conventional practices. This ‘design for adoption’ requires understanding of user motivations, associated beliefs, context of use, and...
Patterns of nest attendance behavior by breeding birds represent a parent-offspring trade-off in which adults balance self-maintenance with parental care decisions.
Incubation, in particular, is of interest because adults must provide an environment
suitable for embryonic development through nest-building and contact-incubation.
We evaluated how adult incubation constancy and nest visitation...