Mammary tumors are the third most common tumor in cats after cutaneous neoplasia and lymphosarcoma. More than 80% of feline mammary tumors are adenocarcinomas, which are similar to human mammary adenocarcinomas in their biologic behavior and histologic characteristics. Despite treatment with radical mastectomy, feline mammary adenocarcinoma is associated with a...
The objectives of this study were to determine the effects of acupuncture in dairy cows on caruncular matrix metalloproteinase type-2 (MMP2) tissue concentration and enzyme activity at 0, 2, and 4 hours after calving. Immediately after natural calving, a caruncle was obtained from the body of the uterus and flash...
This research investigated the development of a novel canine model to study preeclampsia. Normal canine placental development has morphologic and histologic similarities to the shallow trophoblast invasion occurring with preeclampsia in humans, which makes the dog a particularly good choice for modeling this disease and will be an improvement on...
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Michelle A. Kutzler
This research investigated the development of a novel canine model to
In this dissertation, the structure and electronic properties of multiple metal oxide thin films are characterized and presented. Prompt inorganic condensation (PIC) of metal-oxo and –hydroxo clusters was evaluated as a technique for making metal oxide clusters in two separate studies. The first focuses on the synthesis of lithium niobate...
Frailty is a clinical syndrome characterized by decreased resilience to stressors, resulting from dysregulation across multiple physiological systems. Frailty is prevalent in elders and is associated with a wide range of adverse outcomes including death, disability, hip fracture, and falls. In the absence of a gold standard, there is a...
A growing body of research has connected bullying victimization to a number of risk factors in adolescents, including substance use. The current study utilizes Agnew’s revised strain theory as a theoretical framework to examine this relationship, as well as patterns of substance use across gender, race, and mental health status....
The purpose of this thesis was to quantify sperm acrosome associated 3 (SPACA3) protein expression in the ovaries of young (3.0±0.9 months, n=11) and adult (10.4±2.8 months, n=11) queens. It was hypothesized that SPACA3 expression would not differ between age groups. Immunohistochemistry was performed on formalin-fixed, paraffin-embedded feline ovarian sections...
Throughout most of the developed world, surgical sterilization via gonadectomy has become a common tool for combating the overpopulation of unwanted dogs as well as to eliminate the risk of reproductive diseases in pet dogs. In the dog as in other normal adult mammal, the hypothalamus secretes gonadotropin-releasing hormone (GnRH),...
The purpose of this thesis was to determine if an underlying biological cause exists for the exuberant reproductive success in free-roaming unowned (FRU) cats. The hypothesis for this thesis was that FRU tom and queen cats have reproductively adapted to man-made sterilization efforts by lowering the age at which they...
Lodgepole pine (Pinus contorta) forests are widely distributed throughout western North America. However, the lodgepole pine forests of central Oregon are ecologically unique to the region, with a mixed severity fire regime, low cone serotiny, and their occasional presence as a climax species. Most of the research conducted regarding the...