An oral Vibrio vaccine for salmonids was developed.
The vaccine was produced by spray coating lyophilized
formalin-killed whole cells of Vibrio anguillarum (VA LS 1-
74) onto non-pareil sugar beads. Then methacrylic acrylic
acid copolymer (Eudragit L-30D) was applied as an enteric
protective coating.
Using x-ray radiographic techniques, it was...
Compositional data is a type of data where the features are non-negative and always sum to a constant. This type of data is frequently encountered in many fields such as microbiology, geology, economics and natural language processing. Compositional data has unique statistical properties that makes it difficult to apply standard...
The fundamental aim of this study was to determine how Malaysians define both leisure
and recreation. Two ethnic groups, Chinese and Malays, and rural and urban variants of these
groups were included in the sample. The other objective was to determine if there were differences
in the definitions due to...
In order to better characterize linker histone interactions with DNA, avian erythrocyte-specific linker H5 and the trypsin-resistant globular domain of H5 (GH5) were used in DNA binding studies. To begin, H5 displayed a considerably higher binding
affinity for DNA than the isolated globular domain (GH5), supporting the importance of the...
This dissertation delves into understanding, characterizing, and addressing dataset shift in deep learning, a pervasive issue for deployed machine learning systems. Integral aspects of the problem are examined: We start with the use of counterfactual explanations in order to characterize the behavior of deep reinforcement learning agents in visual input...
Cold air pools are spatiotemporal phenomena that occur when cold air from higher elevations roll down the slope to accumulate in lower elevations. Behaviors like this lead to microclimate anomalies such as the city of Corvallis (Oregon) experiencing persistent cold weather even on a sunny day. We analyze multivariate temperature...
Studies were conducted in 1976 and 1977 on the effects of harvest
dates on maturity, yields and sugar content of four cultivars of
sweet corn. The cultivars were 'Golden Cross Bantam', 'Jubilee',
'Rapidpak' and 'Tendertreat'. Moisture content of kernels ranged from
80 to 67 per cent for the six harvest...
Within the past several years the technology of high-throughput sequencing has transformed the study of biology by offering unprecedented access to life's fundamental building block, DNA. With this transformation's potential a host of brand-new challenges have emerged, many of which lend themselves to being solved through computational methods. From de...
The movement characteristics of five landslides are
compared and interpreted based on records of approximately
10-years duration. Condon landslide in the Oregon Coast
Range has consistently exhibited brief (1 - 8 days) movement
episodes in wet winter months, separated by long periods of
no movement. The translatory movement is probably...
This investigation is concerned with the determination of the temperature-effective period (T.E.P.) for crossvein development at physiological temperatures using three isogenic crossveinlesslike (cvl) lines of Drosophila melanogaster.
The method used to determine T.E.P. relies on temperature differences in phenotypes and on a program of transfers from one temperature to another...
In the present study, processed soymilks prepared by various
manufacturing methods were examined for quality by physical and
chemical methods. Viscosity, pH, soluble solids, total solids, fat
and protein content were used as indicators of quality. The principal
factor investigated was the protein content as measured by the
dye-binding procedure....
An experimental study was conducted with beginning typewriting
students to investigate the effects of two variables in proofreading
straight copy paragraph materials in the independent method of
proofreading. One was the influence of repetition which was examined
through the use of three different methods of reading. The second
was the...
Atmospheric carbon dioxide has increased by approximately 40% since preindustrial times from 280 ppm (parts per million) to 400 ppm. The rise in Pco₂ is causing the ocean to become more acidic due to the uptake of carbon dioxide by the water, termed “ocean acidification”. As the Pco₂ in the...
Eight experiments, two with poults and six with chicks, were
undertaken to determine the requirement for supplemental folic acid
as related to protein level and major protein source. Protein levels
for chicks and poults were 21, and 28 or 28 and 32%, respectively.
Major protein sources were soybean meal, fish...
The objective of this study was to quantitatively describe the intrusion of logging debris into artificial gravel streambeds during conditions of low stream flow with a stable streambed, and begin an
analysis of the effect of high flow and unstable streambeds. This study was initiated because prior studies indicated that...
For ras gene mutation analysis in the rainbow trout (Oncorhynchus
mykiss) model system, a partial trout ras sequence was identified
using the polymerase chain reaction (PCR). Two synthetic
oligonucleotides based on rat K-ras gene sequence were used as
primers for the PCR procedure. A 90 base pair (bp) sequence,
referred...
The yeast two-hybrid system was used to examine
interactions between the nine proteins involved in baculovirus DNA
replication. From the six proteins required for DNA replication,
four protein-protein interactions were identified, including an
interaction between LEF-1 and LEF-2, LEF-3 and itself, LEF-3 and
P143 (Helicase), and an interaction between IE-1...
The question of how the presence of nucleosomal
packing of DNA modifies carcinogen interaction at
specific sites cannot be answered by studies on whole
chromatin or bulk nucleosomes because of the
heterogeneity of DNA sequences in the particles. This
problem was circumvented by constructing nucleosomes that
are homogenous in DNA-histone...
The rainbow trout (Oncorhynchus mykiss) model
of chemical carcinogenesis is becoming increasingly
important as a supplement to rodent studies. However,
much of the molecular biology of the carcinogenic
response is still unknown in the trout model. The ras
gene family has been implicated in the tumorigenesis of
both spontaneous and...
Indole-3-carbinol (I3C) and butylated hydroxyanisole (BHA), anti-carcinogens
present in the human diet, were tested for their in vivo
and in vitro effect on aflatoxin B₁. (AFB₁) metabolism, and DNA adduct
formation in the rainbow trout. Dietary BHA at either 0.3 or 0.03%
had no effect on the hepatic tumor incidence...
Anthropogenic carbon dioxide emissions are causing ocean acidification (OA) and ocean warming, which have negative effects on the larvae of many marine invertebrates. Oregon pink shrimp (Pandalus jordani) currently encounter upwelling events that can result in pH values as low as 7.6, and, more recently, marine heat waves that raise...
The work in this thesis has provided conclusive genetic evidence
that "panhandle" intermediates form during adenovirus replication.
Adenovirus chromosomes lacking 51 by from their left -hand termini
are infectious and capable of regenerating the missing origin
sequence. Yet if an entire inverted terminal repeat is removed, the
adenovirus chromosome is...
Many marine bivalves are sensitive to ocean acidification (OA) stress and often show heightened sensitivity during brief early larval and post-larval life stages, potentially leading to population bottlenecks. Most of the evidence to date has been collected in laboratory experiments that focused on physiological responses at the organismal level under...
Learning latent space representations of high-dimensional world states has been at the core of recent rapid growth in reinforcement learning(RL). At the same time, RL algo- rithms have suffered from ignored uncertainties in the predicted estimates of model-free or model-based methods. In our work, we investigate both of these aspects...
In this thesis, we introduce a novel Explanation Neural Network (XNN) to explain the predictions made by a deep network. The XNN works by embedding a high-dimensional activation vector of a deep network layer non-linearly into a low-dimensional explanation space while retaining faithfulness i.e., the original deep learning predictions can...
Object categorization is one of the fundamental topics in computer vision research. Most current work in object categorization aims to discriminate among generic object classes with gross differences. However, many applications require much finer distinctions. This thesis focuses on the design, evaluation and analysis of learning algorithms for fine- grained...
DHA (22:6,ω3), but not EPA (20:5,ω3), attenuates Western diet (WD)-induced hepatic fibrosis in a Ldlr[superscript −/−] mouse model of nonalcoholic steatohepatitis. We examined the molecular basis for the differential effect of dietary EPA and DHA on WD-induced hepatic fibrosis. DHA was more effective than EPA at preventing WD-induced effects on...
Full Text:
cells . —Lytle, K. A., C. M.
Depner, C. P. Wong, and D. B. Jump. Docosahexaenoic acid
attenuates
The rapid increase in atmospheric carbon dioxide (CO₂) over the last 250 years has led to the absorption of approximately 550 billion tons of anthropogenic CO₂ by the global ocean. This oceanic uptake of CO₂ has resulted in decreasing pH and alterations to carbonate chemistry, threatening many ecologically and economically...
Lepidopteran nucleopolyhedroviruses are members of the Baculoviridae and have been categorized as having two morphotypes of occluded virions: multiple nucleocapsids or single nucleocapsids within the virion envelope. Although it is a definitive characteristic of specific viruses, it appears to lack a defined genetic basis and is independent of virus phylogeny....
Throughout the Holocene, appreciable changes in bathymetry are hypothesized to have resulted in large changes to tidal datums in coastal and estuarine areas. An understanding of tidal change is an important contribution to the knowledge of relative historical sea-level change and future coastal planning. To test this hypothesis, the Advanced...
I have participated in a drug discovery program designed to screen marine algae for
inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances,
and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts
of marine plants and animals were surveyed for biomedical potential. Assays designed to
screen extracts...
Little is known regarding the catabolic mechanisms involved
in the breakdown of glucose in mung bean (Phaseolus aureus)
seedlings. Studies in other laboratories have shown that the TCA
cycle pathway is operative in mung bean leaves, and have demonstrated
the presence of enzymes for the oxidation of glucose to
glucuronic...
In this comprehensive thesis, we present a series of experiments and findings that highlight the
critical importance of TDC Voltage Sensors in the hardware security domain. Our research begins
by introducing a novel self-calibrating module, demonstrating its efficiency through preliminary
calibration tests. We then delve into the Peak-to-Peak tests, which...
Purpose: The general problem was to determine the relationship between biorhythms and injuries to college football participants representing Oregon State University. Procedures: The population consisted of one hundred and ninty two football players representing Oregon State University who participated in the intercollegiate football seasons of 1981 and 1982. Injury data...
In this thesis, we investigated the surface composition and orientation of both pure room-temperature ionic liquids (Ils) and binary mixtures of the ILs of the type consisting of the 1-alkyl-3-methylimidazolium ([C[subscropt n]mim]⁺, n=4, 8, and 12) cation coupled with either [PF₆]⁻, [BF₄]⁻, [Cl]⁻, or [Br]⁻. The surfaces of the ILs...
When contributing to a software system, developers need to understand the rationale for previous design decisions so that they can adhere to the system’s design. Not doing so can lead to erosion of the overall design quality of the system. However, discussions embedded in a large volume of communication on...
The climate of the Pacific Northwest is in flux, and existing forest ecosystems are stressed and poised to shift in fundamental ways, with or without human intervention. This dissertation probes the nature of forest responses to environmental change through investigations of morphology and genetics of three species of alder co-occurring...
With the advent of Artificial Intelligence (AI) in every sphere of life in today's day and age, it has become increasingly important for non-AI experts to be able to comprehend the underlying logic of how AI systems work, assess them and find faults in these systems, particularly when they are...
We consider the problem of supervised classification of bird species from audio recordings in a real-world acoustic monitoring scenario (i.e. audio data is collected in the field with an omnidirectional microphone, without human supervision). Obtaining better data about bird activity can assist conservation efforts, and improve our understanding of their...
During catalysis the flavoprotein domain of neuronal nitric-oxide synthase (nNOS) shuttles NADPH-derived reducing equivalents from FAD to FMN and then to the P450-heme enabling heme-based oxygen activation and subsequent NO-synthesis. The binding of Ca²⁺-activated calmodulin (Ca²⁺-CaM) to nNOS alleviates inhibition of flavin mediated electron transfer within the diflavin domain, which...
Multiagent learning offers a rich framework to address challenging real-world problems such as remote exploration and healthcare coordination, which require autonomous agents to express elaborate interactions. To be effective in such systems, agents must collectively reason about and pursue high-level, long-term, and possibly nebulous objectives while adapting their strategy to...