Background
Feline injection-site sarcoma (FISS) is a rare and aggressive tumor associated with vaccines, drug injections, and skin trauma in cats. The understanding of FISS remains limited, posing challenges in its diagnosis, treatment, and prevention. In this study, we analyzed the differential expression of miRNAs and their target genes in...
Wheat is an important part of a healthy and balanced diet, requiring six servings per day to maintain a recommended 2000 Calorie intake (McRae, 2017). Because of this more land than almost any other kind of cereal is set aside for the purposes of growing wheat. To keep up with...
Onion thrips (Thrips tabaci) are pests found in onion fields of the Treasure Valley, which is located in Eastern Oregon and Western Idaho. Thrips cause damage to this high value crop by feeding on the onion’s extracellular fluid, making photosynthesis more difficult to occur. The feeding from the thrips can...
There is a growing need to establish alternative approaches for assessing hazard from chemical exposure compared to the traditional method of animal testing. Approaches that relate chemical structure to biological activity are gaining acceptance in the field as in silico methods for characterizing and predicting chemical toxicity. In this study,...
Phytophthora ramorum is the causal agent of Sudden Oak Death (SOD), which is an economically and environmentally important disease causing up to 80% mortality of tanoaks in Pacific Northwest coastal forests (LeBoldus et al., 2022). There are currently four clonal lineages in the United States and Europe, named North America...
Sweetpotatoes are a highly nutritious staple crop, playing an important role in global nutritional security. Although the majority of research in the United States (U.S.) focuses on the cultivation of the storage roots, both the leaves and roots are edible. Sweetpotatoes are indigenous to the Andes Region of South America;...
Female dairy cattle are particularly prone to infertility/subfertility with pregnancy rates ranging as low as 27% to a high 40%. On average it takes more than one breeding/insemination event for dairy cattle to become pregnant. This results in a loss of the number of calves a female would have per...
Infertility is an issue affecting millions of women across the globe, yet the causes are not fully understood, and treatment options are often ineffective. The evaluation of reproductive hormones has been a common tool used by fertility clinics as a way to predict the ovarian response to treatment and gain...
To evaluate and monitor insecticide resistance in onion thrips Thrips tabaci on onion (Allium cepa), we conducted a study using three field populations in the Treasure Valley of eastern Oregon and southwestern Idaho using the insecticides Lannate (methomyl) and Exirel (cyantraniliprole). To evaluate these two insecticides, biological assays were conducted...
Polycyclic aromatic hydrocarbons (PAHs) are a known class of chemicals that are linked to a multitude of adverse health outcomes. There are over 1,500 of these chemicals across various families and subgroups. 16 of these PAHs, known as parent PAHs, are identified by the EPA for focused risk assessment within...
Pacific Northwest temperate rainforests are anticipated to experience increasingly frequent and severe wildfires in the foreseeable future due to climate change, increased fuel loads, and deforestation. Soil, underlying these forests, is the largest terrestrial carbon (“C”) reservoir. Fire disturbance influences soil C persistence, the timeframe and magnitude of which remain...
Testing the many potential chemoprevention agents from dietary sources in animal or human models is expensive and takes a long time. In vitro models can be useful for screening the right compounds to use in larger studies. We tested the MatTek™ EpiIntestinal™ small intestine epithelial 3D cell culture model for...
Volatile organic compounds (VOCs) play an integral role in climate change and as a carbon source for organisms living in a marine environment. These compounds have many sources, but the impacts of biogenically produced VOCs is not fully known. Phaeodactylum tricornutum was studied under axenic ideal growth conditions to determine...
Background: The immune response to microbial infections is compromised in beef cattle at parturition. Innate and adaptive immunoglobulin M (IgM) serve as initial antibodies during microbial infection before the generation of adaptive immunoglobulin G (IgG). Selenium (Se) is an essential micronutrient required by all mammals, which can improve immune responses...
The COVID-19 pandemic highlighted disparities in land access and food security. Research has shown that access to gardening reduces financial burdens on low-income households. Compared to homeowners, individuals and families in rental housing face added barriers to vegetable gardening and growing food. These barriers include rental housing regulations and the...
Microplastics (<5mm) are a ubiquitous environmental pollutant that have the potential to cause significant harm in many fish species. Therefore, understanding the quantities at which they are being consumed by living organisms is crucial for characterizing risk. There are currently gaps in the microplastic literature regarding microplastic data from finfish...
Soil contains approximately 75% of the carbon pool on land - three times more than the amount stored in living plants and animals (Schlesinger 1999). Therefore, soils play a major role in maintaining a balanced global carbon cycle. Models of the soil carbon ecosystem assume a strong relationship between organic...
Background: Uterine inflammation (e.g., endometritis) causes negative economic effects in the beef industry by reducing reproductive performance. Current treatments for endometritis in beef cattle involve hormones and antibiotics, which can be expensive and are often ineffective. The endometrial immune response regulates the release of cytokines and chemokines in response to...
The decline of the Chinook Salmon has been a mystery of recent years due to their decline. It has been speculated that wild origin salmon have more vigor and survivability than hatchery reared fish. This is thought to be due to rearing conditions, possibly affecting sensory organ development. The sensory...
Hatcheries are used to produce salmon to augment the number of fish available for harvest, and to supplement wild populations that may be threatened with extinction. Although traditional hatchery rearing methods can produce many fish, they can pose risk to wild populations because they tend to produce salmon with lower...
Polycystic Ovary Syndrome (PCOS) is an idiopathic disorder prevalent in ~5-10% of reproductive-aged women. In PCOS women who become pregnant, many experience complications including increased susceptibility of having a miscarriage, high blood pressure, and gestational diabetes, among others. Additionally, exposure to PCOS may have transgenerational impacts: offspring may be at...
STEM education is delivered to K12 audiences by Pre-college Programs across the nation, many of which serve underrepresented and underserved students as part of their core missions. While there is robust attention to STEM curriculum development and college connection events in such programs, few have social-cultural aspects of learning as...
Vitiligo is a disease characterized by depigmented patches of skin. The disease is known to involve the loss of melanocytes in the basal layer of the skin in affected areas, but the underlying mechanisms are unknown. Recent evidence suggests oxidative stress and disruptions to antioxidant pathways contribute to an autoimmune...
Anaerobic digestion is a common terminal step in wastewater treatment systems and produces valuable by-products such as biogas, a combination of carbon dioxide and methane. Biogas can be used to off-set energy costs, and along with the anaerobic co-digestion of fats, oils, and greases (FOG) has been found to increase...
The United Nations Food and Agriculture Organization (FAO) in the State of World Fisheries and Aquaculture 2018, has observed that the trend of the world’s marine fish stocks has been overexploited, depleted, and has exhibited decreasing trend within the fraction of biologically sustainable levels. While these situations are an alarming...
Top predators play important roles in regulating communities and ecosystem processes in freshwater ecosystems. In the headwater stream network, it is crucial to understand the interspecific interaction between multiple predators. In Oregon forested ecosystems, Coastal Giant Salamander (Dicamptodon tenebrosus) and cutthroat trout (Oncorhynchus clarkii) are the top predators in many...
Acetaminophen (APAP) is a commonly used analgesic and antipyretic drug that can cause liver injury, liver necrosis, and liver failure. APAP-induced liver failure (AILF) is associated with depletion of glutathione and the increased formation of APAP protein adducts from the toxic NAPQI metabolite. There is a hypothesized detoxifying pathway where...
Blueberry stem galls in Pacific Northwest are often attributed to Agrobacterium tumefaciens. The disease also is associated with indole-3-acetic-acid (IAA) producing bacteria, as described on cranberry stem gall. Lack of studies makes it difficult to conclude whether these two types of bacteria could be the causal agent of stem gall...
The variability of heavy metal concentrations (Pb, Cd, Zn, and Cu) of the terrestrial moss Orthotrichum lyellii on single trees was evaluated at two sites in the Pacific Northwest, one relatively unpolluted and the other polluted. In addition, a reciprocal transplant of O. lyellii between the unpolluted and polluted sites...
Benzo[a]pyrene (B[a]P) is a common environmental pollutant produced from the incomplete combustion of organic matter, such as fossil fuel emissions. In vertebrates, B[a]P exposure is associated with hyperactivity, though the underlying mechanisms driving this effect are undescribed. Mounting evidence indicates that the gut microbiome, which is the diverse community of...
Succinate dehydrogenase (Sdh) inhibitor fungicides, such as boscalid, are effective for the management of gray mold caused by the fungal pathogen Botrytis cinerea. Unfortunately, resistance to boscalid was common among isolates of the pathogen from small fruits grown in Oregon. Boscalid-resistance is commonly associated with mutations in Sdh, especially in...
Biogas can be used to generate energy from a wide variety of sources. Wastewater treatment sludge is an effective source of waste to be used for generation of biogas to make energy which can be used to heat homes and run businesses. This would help decrease the use of fossil...
Oregon is the number three producer of strawberries in the nation despite the fact that Oregon strawberry acreage dropped from 2,600 acres in 2005 to 2,000 acres in 2014 (Beeles, 2015; NASS, 2019, Losh, 2017). With over three billion pounds of berries grown nationally each year, strawberries are an important...
Endophytes, foliage inhabiting fungi, are an unexplored source of fungal biodiversity and a potential resource for the production of bioactive natural products. In this research, leaf tissues from the species Arbutus menziesii, Rhododendron macrophyllum and the genus, Ilex and Salix were collected for the isolation of endophytic fungi. Fungal extracts...
Postpartum uterine inflammation (endometritis) is not uncommon in beef cattle, resulting in infertility and culling. Prolonged calving may contribute to the increased incidence of endometritis in heifers. Commonly used methods to treat endometritis in beef cattle include intrauterine antibiotics and/or hormone injections, which can result in meat residues. Platelet rich...
Bacterial endophytes have the potential to confer benefits to Douglas-fir ( Pseudotsuga menziesii ), for instance drought tolerance. Bacterial endophytes originating from seeds are especially important. This is because seed endophytes are more likely to be the first endophytes to get established within the young host plant. The goals of...
Phytochemicals from the genus, Fagonia, have been attracting increasing attention due to their potential beneficial effects on human health, particularly, anti-cancer properties. Certain Fagonia species contain various types of phytochemicals such as saponins, alkaloids, cardiac glycosides, flavonoids, terpenoids, and tannins. In this study, we investigated the phytochemical composition of a...
Energy production and consumption is a major environmental and economic concern in the world today. Biofuel produced from lignocellulosic biomass is being explored as an alternative energy source to petroleum. Lignocellulosic biomass is comprised of cellulose, hemicellulose, and lignin. To produce biofuels, lignocellulosic biomass must be broken down to expose...
Due to public and regulatory restrictions, genetic containment technology is critical for research and development of transgenic trees in forestry. A multi-year field trial demonstrated that the RNAi-LFY construct successfully induces sexual sterility in 6K10 poplar (Populus alba) without visible effects on vegetative development. However, its limited number of replicates...
Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
In current nanotoxicology research, there is a lack of standardization in reporting of zebrafish exposure media and sonication practices. This lack of standardization in use and reporting methods has made reproducing nanoparticle (NP) toxicity results between labs a common issue. It is important to have a standardized way of reporting...
There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants due to the incomplete combustion...
In order to reduce the cost of lignocellulosic ethanol production, a model was previously developed to predict the amount of fermentable sugar released based on parameters concerning both biomass and enzymes. To validate this model, enzymatic hydrolysis must be carried out using individual purified cellulase enzymes. Endo-1,4-β-D-glucanase I (EG I),...
The prevalence of obesity and diabetes in the United States and globally has been rising in the last few decades and it continues to climb. One of the causes for this increase is the over consumption of sugars and/or carbohydrates. Among medications available to treat obesity and diabetes are the...
As engineered nanomaterials (ENM) become more common in consumer products, it is crucial to rapidly assess toxicity of unique ENM. Previous studies rarely focused on standardizing nanotoxicity testing, leading to inconsistent and irreproducible results. This study characterized a variety of ENM of different size, shape, core type, and surface charge...
Canine Transitional Cell Carcinoma (TCC) makes up 2% of all canine cancers and is the most common cancer of the bladder for dogs. Usually diagnosed in its later stages, TCC is difficult to treat, with low survival times. Current diagnosis involves invasive techniques, and mainstream screening tests are often ineffective....
Feeding cows flaxseed rich in polyunsaturated fatty acids has been shown to decrease the proportion of saturated fatty acids and increase the proportion of n-3 polyunsaturated fatty acids (PUFAs) in milk. Consuming products enriched in n-3 PUFAs have beneficial effects to human health; thus, feeding cows flaxseed could potentially increase...
Fungicide sensitivity of honey bee associated fungi
Abstract - Honey bees are exposed to a wide range of pesticides while pollinating agricultural crops. These pesticides residues are found in beeswax, nectar and pollen in the hive. Some of the pesticides found are fungicides which are not generally considered harmful to...
Cyanophage are viruses that infect cyanobacteria, photosynthetic microorganisms which are known to produce several anticancer and antibacterial chemical compounds. Cyanophage are significant members of microbial communities in marine and freshwater environments. There has been significant difficulty inventorying marine and freshwater cyanophage, however, due to the difficulty in cultivating their hosts....
Modifications of histone tail amino acid residues are necessary for many reactions involving chromatin. These processes can produce transcriptionally active, euchromatic, or inactive, heterochromatic, segments of DNA. The formation and maintenance of facultative heterochromatin is critical for the proper growth and development of many eukaryotes. Euchromatin can be changed into...
Microbial electrolysis cells (MECs) for hydrogen production exhibit great advantages over many other biohydrogen production techniques in terms of versatility of substrate and hydrogen yield. However, hydrogen scavenging by methanogens put forward a great challenge to the application of the single chamber MECs when using mixed culture. Various strategies were...
Vibrio cholerae a major health problem in developing countries because of its ability to cause the disease cholera in humans. As V. cholerae bacteria are common inhabitants of temperate marine and brackish water environments worldwide, they are subject to intense top-down pressure by amoebae, which can affect their survival and...
Western diets can influence behavior and gut microbiome due to the excessive intake of high fat and sucrose. Altering the microbiome can also influence the brain and behavior. The hypothesis that was tested was that diet-induced changes in the microbiome cause changes in cognitive abilities. A previous study showed learning...
Columbia Glacier, Alaska’s most rapidly retreating body of ice, provides a compelling insight into the fragile state of tidewater glaciers worldwide. Catastrophic retreat of the glacier’s terminal ice margin began in 1978 when contact was lost with its stabilizing terminal moraine shoal. Since this time, Columbia Glacier has lost ~20...
Bio-oil from hydrothermal liquefaction (HTL) represents a promising fuel source due to large higher heating values and compatibility with current energy infrastructure. For bio-oil production to become commercially viable, novel methods of co-product recycling must be explored.
The aims of this study were to culture Chlorella vulgaris, a common HTL...
The hypothalamic neuropeptide kisspeptin (Kiss-1) acts as a central component of the reproductive axis. A critical factor in pubertal progression and normal reproduction, this peptide is an afferent stimulator of gonadotropin-releasing hormone (GnRH), and is responsive to gonadal steroids, integrating steroid hormone signals and modulating GnRH secretion accordingly. Kiss-1 exhibits...
Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
4-H, an agriculture based youth program, promotes a variety of curricula in both agriculture and Science, Technology, Engineering and Math (S.T.E.M.) topics. However, science based curricula provided by this organization gravitates away from the programs agricultural roots. An effort was made to pilot a test on lesson plans that would...
Gene expression in plants (and other eukaryotes) is a very complex process. Gene expression is primarily controlled by proteins and their binding sites near the gene in the chromosomal DNA. More specifically, interactions among transcription factors (DNA-binding proteins) and cis-regulatory modules (CRMs-sets of binding sites) control the expression of nearby...
Embryonic development, where organs and major structures begin to develop, requires precise coordination of numerous gene regulatory pathways. Fendrr is an long non-coding RNA (lncRNA) that plays a role in regulating gene expression in mesodermal tissues during early embryonic development in mouse. The lateral plate mesoderm (LPM) is an earlier...
The Bcl-2 family of proteins regulate cell survival and are targets for cancer therapy. This protein family has also been implicated in chemotherapeutic resistance, the cause of approximately 90% of treatment failure in advanced cancer. We analyzed the expression and the role of the Bcl-2 proteins in chemotherapy resistant breast...
Vibrio cholerae (Vc), the etiological agent of cholera, has developed many mechanisms to combat the great fluctuations in pH, ion content and osmotic conditions of the vastly differing environments it encounters through its infections of the human host. A series of cation antiporters are found in the Vc membrane to...
The use of zebrafish in behavioral neuroscience is rapidly growing. Zebrafish can be assessed for alterations in multiple behavioral endpoints, creating opportunities to use this powerful model to identify chemicals that alter behavioral phenotypes. To evaluate the utility of zebrafish for neurotoxicity research, we designed custom instrumentation to evaluate numerous...
Liquid manure lagoons are known to be sources of odor and environmentally damaging gas emissions. Land application of the manure slurry after storage can lead to detrimental nutrient runoff and leaching. Floating lagoon covers (biocovers) are one option for reducing emissions, but to date they have only been used to...
Lung cancer in humans is an adult-onset disease. It is the number one cause of cancer mortality for both men and women and has a poor (15%) survival rate. Biological markers of the disease would allow for early diagnosis and treatment. The specific aims of this research project were to...
This study examines climatological influences, particularly that of snowpack, on tree growth and stable carbon isotope discrimination (Δ¹³C) from ~1980 to 2013 at two sites located in the upper reaches of the McKenzie River watershed of the Oregon Cascade Mountains. We tested the use of Δ¹³C values from latewood, corroborated...
Infestations of container nursery beds by Phytophthora spp. can be persistent and costly. One method of disinfestation that does not require the use of chemicals is soil solarization, which captures energy from the sun to heat soil and thermally inactivate target pathogens. In laboratory temperature gradient experiments, I investigated the...
Fungicide sensitivity of honey bee associated fungi
Abstract - Honey bees are exposed to a wide range of pesticides while pollinating agricultural crops. These pesticides residues are found in beeswax, nectar and pollen in the hive. Some of the pesticides found are fungicides which are not generally considered harmful to...
Budburst, the initiation of annual growth in plants, is sensitive to climate variation and is therefore used to monitor physiological responses to climate change. Budburst timing can vary between regions of an individual tree, but this phenomenon it is unaccounted for in current monitoring efforts and may contribute to the...
Anaerobic digestion of lipid-extracted algal biomass has been proposed as a method to
recover and recycle nutrients in algal biofuel systems. The purpose of this study was to quantify recoverable nitrogen and phosphorus from anaerobically digested C. vulgaris. Recoverable nutrients were deemed those present in the liquid phase of anaerobic...
Colorectal cancer (CRC), the third leading cause of cancer death in the USA, depends on early detection for patient survival. Early detection is improved with the identification of high risk individuals. Risk of CRC development is a complex interaction between an individual’s genetics and environmental exposures. Polycyclic Aromatic Hydrocarbons (PAHs)...
Extraction of natural gas from shale formations using the process of hydraulic fracturing (fracking) requires the use of thousands of cubic meters of fluid. Hydraulic fracturing fluids are pumped under pressure into shale formations, fracturing the shale and releasing pockets of trapped gases. When the pressure in a natural gas...
Lignocellulosic biomass has potential as a renewable resource for global energy and bioproducts production. Biomass consists of three main polymers, cellulose, hemicellulose, and lignin. Cellulose is a homopolymer of glucose, while hemicellulose and lignin are heteropolymers. Lignin is primarily made of syringyl (S), guiacayl (G) and p-hydroxyphenyl (H) units. Pretreatment...
Abstract
Flame-retardants (FRs) generally enter the environment by dissociating from the products they were originally manufactured into. The predominant class of FR used in consumer products before their eventual phase-out in the mid-2000s were the polybrominated diphenyl ethers (PBDEs). Previous studies have illustrated a correlation between socio-economic status, notably gross...
Oregon White Oaks (Quercus garryana) were once abundant in the Willamette Valley, Oregon, but have drastically decreased because of fire suppression, agriculture, and human development. Oaks are an important ecosystem because they provide a diverse habitat for bird species that are insectivorous and/or cavity nesters. We studied the oak restoration...
Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...
This study examines climatological influences, particularly that of snowpack, on tree growth and stable carbon isotope discrimination (Δ¹³C) from ~1980 to 2013 at two sites located in the upper reaches of the McKenzie River watershed of the Oregon Cascade Mountains. We tested the use of Δ¹³C values from latewood, corroborated...
The synergetic interplay between the removal of saturated methyl esters and the addition of deoxygenated fatty acids on depressing the cloud point temperature of biodiesel was investigated in this study. Canola biodiesel was produced in batch as a standard with a cloud point of 1.37 +/- 6.3°C. Saturated methyl esters...
There are a number of problems associated with urban expansion and as cities continue
to grow the integration of green roofs can help to ease and offset many of them. This study
uses a combination of moss and Sedum as vegetation for experimental green roof sections in
order to test...
Knowledge of Drosophila suzukii's preference for an attractive trap design and bait can be used to improve detection and management of this new invasive fruit pest. Desired trap and bait attributes include: high D. suzukii capture and species specificity; early-season detection prior to significant crop damage; higher capture of females...
Hart Mountain National Antelope Refuge (HMNAR) established in 1936, is 101,000 ha in area. The refuge was grazed by domestic livestock from the 1870s until their exclusion in 1990. Just prior to removal of livestock, photopoints were taken at various riparian and wetland locations throughout the refuge to document riparian...
Hypoxia is a naturally occurring phenomenon that happens seasonally off the Oregon coast. As a consequence, there has been a great deal of research focused around analyzing the strength and duration of the hypoxic event during the summer season. This paper, however, takes an innovative approach by looking at the...
Humans and rodents experience declines in reference (long-term) and working (short-term)
memory and cognitive flexibility during the aging process. Aging changes in GluN1 and
GluN2B subunits of N-methyl-D-aspartate (NMDA) receptors show a relationship to both
reference and working memory deficits. Sulindac, an anti-inflammatory drug, enhances working memory and NMDA receptor...
Pactamycin, a complex aminocyclitol compound produced by Streptomyces pactum, has significant antibiotic, antitumor, and antiplasmodial activity. However, this natural product has not been developed for clinical use due to its high cytotoxicity. Modulation of its biological properties by chemical synthesis has been difficult due to its complex chemical structure. Therefore,...
As scientific technologies and techniques have improved in past decades, it has become
possible to quickly collect unprecedented quantities of experimental data. In the study of gene expression, for instance, datasets comprising tens of thousands of variables and hundreds of treatments can be produced in a matter of months. When...
Zinc is an essential micronutrient required for many cellular functions, including
the development and function of the immune system. The biological consequences of
zinc deficiency illustrate the significance of zinc in human health. Zinc deficiency has
been shown to cause the dysregulation of both innate and adaptive immune responses, as...
Abstract Understanding small-scale bio-atmospheric interactions is becoming increasingly important as the global climate continues to change at breakneck speed.
A theoretical model of the sensible heat budget of a forest is developed combining
conservation equations and concepts from fluid dynamics. Budget components are
computationally evaluated using micrometeorological data taken during...
Four root mutants, diageotropica (dgt), and altered root architecture (ara) 1, 2, and 3, were used to study root architecture and better understand the process by which root architecture is determined. Adventitious root formation, tissue response to auxin, nutritional response, and starch accumulation in the leaves were tested in ara...
Greenhouse gases effects are a leading contributor to climate change; reducing harmful effects of these gases is important for future generations. Worldwide, household consumption makes up seventy-two percent of greenhouse gas emissions, followed by government consumption at ten percent, and investments at eighteen percent (Hertwich, 2009). In order to understand...
Flour aging is thought to occur naturally during storage of wheat flour. In soft-wheat it is hypothesized that aging may increase water absorption properties of the flour. The aim of this study was to determine if the absorption capacity of flour changes as a response to flour aging. Absorption was...
To initiate the defense response to an invading pathogen, plants utilize an array of immune receptors to recognize virulence effectors. Virulence effectors are released by pathogens to suppress immune responses in target hosts. These effectors are recognized by a family of resistance proteins known as nucleotide-binding leucine-rich repeat (NB-LRR) proteins....
Stringhalt is a disorder in horses characterized by high stepping with hyperflexion of the hind limbs. This disorder has been reported from the US, Australia, Chile, and Brazil. In most instances, the disease manifests itself in horses exposed to summer dandelion (Hypochaeris radicata). Stringhalt has been induced by feeding summer...
Respiratory Syncytial Virus (RSV) is a major concern in infants, the elderly, and immunocompromised individuals. There is currently no vaccine available. While it causes a significant number of hospitalizations and complications, RSV is a thermo labile virus and not very stable in the environment. This matter complicates the creation of...
Cancer economic impact is enormous and depending on the stage in which a colon cancer
is detected, five-year survival rates for colon cancer may be as high as 74%, or as low as
6% (American Cancer Society, 2012). Thus early prevention of colon cancer is crucial to
maximize the chances...
The Willamette Valley, west of the Cascade mountain range in the state of Oregon, is home to a growing number of vineyards. This rather recent, booming industry of the region has become an important component of the economy of the state’s agriculture since the late 1960’s, contributing more than $1.56...
The Willamette Valley, west of the Cascade mountain range in the state of Oregon, is home to a growing number of vineyards. This rather recent, booming industry of the region has become an important component of the economy of the state’s agriculture since the late 1960’s, contributing more than $1.56...
Summary
Recent research has identified Retinoid-X-Receptorα (RXRα), a nuclear receptor involved in ligand mediated transcription, as having a protective function against the malignant transformation of melanocytes after treatment with chemical carcinogens. This study used mice selectively lacking keratinocytic RXRα in combination with an oncogenic mutation, either Cdk4[Superscript R24C/R24C] or N-Ras[Superscript...
Toxicological studies show that oral doses of nickel can cause allergic contact dermatitis, and routes of exposure, such as nickel leached from stainless steel cookware are not well characterized. In this study, four variables: grade of stainless steel, cook time, stainless steel seasoning or cooking cycles, and commercial tomato sauces,...
We compiled Western Pond Turtle (Actinemys marmorata) and Painted Turtle (Chrysemys picta) locations in northwestern North America, consolidating data from multiple sources including nine U.S. State and Canadian Provincial jurisdictions. We assessed numbers of discrete locations, and analyzed distribution patterns temporally and spatially. Western Pond Turtle observation records ranged from...
Genetic and environmental factors influence individual cancer risk. Mutations in DNA mismatch repair (MMR) genes increase colon cancer risk. Exposure to carcinogens, including the ubiquitous polycyclic aromatic hydrocarbons (PAHs), also is associated with increased cancer risk. To understand the combined effects of both environmental exposures and genetic risk, we investigated...