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Filtering by: Creator Chen, Tsu-fang Remove constraint Creator: Chen, Tsu-fang Degree Level Bachelor's Remove constraint Degree Level: Bachelor's

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  • Second Derivative Excitation Emission Resolution (SEC DEER) Spectroscopy

    Creator:
    Rosene, Benjamin L.
    Abstract:
    Fluorescence spectroscopy is a powerful analytical technique due to bright signals that provide excellent measurement sensitivity. Many colors of fluorescent dyes are available to match the detection ranges of different equipments. Dyes can be chemically modified to bind to many different target analytes with high specificity1. Alternatively, sensors can be...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Chong Fang, Committee Member, representing Department of Chemistry

  • Molecular Dynamics on REX-GECO1 Reveal Structural Features Governing Fluorescence

    Creator:
    Rozanov, Nikita
    Abstract:
    Fluorescent proteins have emerged as an essential toolset for bioimaging, creating a demand for engineering proteins with new and improved fluorescent properties. In this thesis, I explore the atomistic structure of REX-GECO1, a newly engineered protein biosensor that has unique optical properties. Since this protein has no available crystal structure,...
    Resource Type:
    Undergraduate Thesis
    Full Text:
    Features Governing Fluorescence Abstract approved: Chong Fang Fluorescent proteins have emerged as an

  • Predicting Protein-Protein Interactions in a Cnidarian Model System

    Creator:
    Gregory, Dylan B.
    Abstract:
    The symbiotic sea anemone Exaiptasia diaphana (Aiptasia) is a model organism used to better understand cnidarian-algal symbiosis and coral bleaching (dysbiosis). Many biological processes are hypothesized to be involved in coral dysbiosis, and the innate immunity is a key area of interest. Rab proteins are small proteins with GTPase domains,...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Chen, M.-C., Cheng, Y.-M., Hong, M.-C., & Fang, L.-S. (2004). Molecular cloning of Rab5 (ApRab5) in

  • Differential Binding and Structural Properties of the WWC Protein Family

    Creator:
    Rodriguez, Diego Javier
    Abstract:
    The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...
    Resource Type:
    Honors College Thesis
    Full Text:
    pathway (Chen and Liu, 2018; Han et al., 2018; Han et al., 2017; Hou and Zhou, 2017; Wennmann et al

  • Transformers for representing microbiome data: an empirical evaluation

    Creator:
    Varma, Rohan
    Abstract:
    As the link between human microbiomes and health has become more established, the interest in applying statistical approaches to microbiome data to understand the mechanisms behind these links has grown. However, microbiome data is often of unmanageable size, and consequently, producing quality lower dimensional representations of samples is a significant...
    Resource Type:
    Honors College Thesis
    Full Text:
    ://www.sciencedirect.com/science/article/pii/S0889159115001105 [3] P. Zheng, B. Zeng, C. Zhou, M. Liu, Z. Fang, X. Xu, L

  • Characterizing the Interaction between BCL11B and TCF-1 transcription factors in the control of the BCL-xL gene

    Creator:
    Nagra, Alamjit K.
    Abstract:
    Immature T cells, known as thymocytes, undergo development through successive stages in the thymus and the periphery to become functional mature T cells. These stages are regulated by sequence specific transcription factors (SSTFs). Two such SSTFs, BCL11B and TCF-1, are both known master regulators of thymopoiesis, which is also known...
    Resource Type:
    Honors College Thesis

  • Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish.

    Creator:
    Pryor, Joseph Brian
    Abstract:
    Dendrimers are well-defined, polymeric nanomaterials currently being investigated for their biomedical applications. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The objective of the present study was to investigate the role of surface charge and generation...
    Resource Type:
    Honors College Thesis
    Full Text:
    -370. 22. Chen H-T, Neerman MF, Parrish AR, Simanek EE. Cytotoxicity, Hemolysis, and Acute in Vivo

  • The Effects of UV Irradiation on the Biosorption of Titanium Dioxide Nanoparticles to Heterotrophic Biomass

    Creator:
    Young, William M.
    Abstract:
    The production of titanium dioxide (TiO2) nanoparticles has increased significantly in the past decades, which has generated concern due to their known toxicity in the environment. As a result of the production, use and disposal of productions containing TiO2, TiO2 nanoparticles are often received by wastewater treatment facilities. The adsorption...
    Resource Type:
    Honors College Thesis

  • Sonification as a pathway to knowledge

    Creator:
    Fitch, Russell Alan
    Abstract:
    This paper explores the use of sonification, the conversion of data into sound, to convey the significance of SARS-COV-2 and its global impact. It emphasizes sonification as a valuable tool for making complex data accessible, particularly in high school education. Sonification, an interdisciplinary field, leverages the human auditory system's pattern...
    Resource Type:
    Honors College Thesis
    Full Text:
    are an important factor. These changes may be difficult to fully capture through visual means (Fang

  • The one-child policy and the empowerment of Chinese women

    Creator:
    Li, Yi
    Abstract:
    When people talk about the one-child policy in China, it always relates to topics like human rights violations or the population control dilemma. The one-child policy was published in the 1980s, around the same time as the Economic Reform, and these twin policies brought Chinese society tremendous changes. This paper...
    Resource Type:
    Honors College Thesis
    Full Text:
    , 2019), p.312. 9 ​Chung-hwa Ching, Han-Seng Chen, etc. “Women Drive Teams in Peking”, China