During the 2003 summer monsoon, the Hi‐CLIMB seismological stations deployed across the Himalayan Range detected bursts of high‐frequency seismic noise that lasted several hours to days. On the basis of the cross correlation of seismic envelopes recorded at 11 stations, we show that the largest transient event on 15 August...
Grid-scale energy storage systems are urgently needed to increase the flexibility and rigidity of the grid for modern society and take full advantage of the renewable green energy resources such as solar energy and wind energy. Na-ion batteries (NIBs) and K-ion batteries (KIBs) have been emerged as one of the...
Coral reefs form vast ecosystems in tropical oceans that are hotspots for biodiversity and are economically valuable. The ecological success of coral reefs is made possible by the symbiotic relationship between corals and dinoflagellate algae from the family Symbiodiniaceae. In this symbiosis, the algae are found within host gastrodermal cells...
Treatment providers seek low-cost, high-impact means of engaging clients in care with the aim to enhance treatment delivery and outcomes. With improvements to mobile technology making cell phone accessibility and usage rates high across all socio-economic levels, text messaging is becoming more frequently utilized as a means of promoting provider-client...
The aggregation of 12 nm citrate-stabilized gold nanoparticles (cit-AuNPs) in the presence of four
different natural organic matter (NOM) isolates and a monovalent electrolyte (KCl) was evaluated using
time-resolved dynamic light scattering. All four NOM isolates stabilized the cit-AuNPs with respect to
aggregation. However, specific effects varied among the different...
This dissertation has two objectives. The first objective is to determine where best to situate the study of mentoring (i.e. the 'making of scientists') on the landscape of the history of science and science studies. This task is accomplished by establishing mentoring studies as a link between the robust body...
As the link between human microbiomes and health has become more established, the interest in applying statistical approaches to microbiome data to understand the mechanisms behind these links has grown. However, microbiome data is often of unmanageable size, and consequently, producing quality lower dimensional representations of samples is a significant...
The metal organic framework, MOF-74(Ni), was synthesized in a continuous flow microwave-assisted reactor obtaining a high space-time yield (~90 g h⁻¹ L⁻¹) and 96.5% conversion of reagents. Separation of the nucleation and growth steps was performed by using uniform and rapid microwave heating to induce nucleation, which allowed a substantial...
Herein, we report the successful development of a novel nanosystem capable of an efficient delivery and temperature-triggered drug release specifically aimed at cancer. The water-soluble 130.1 ± 0.2 nm iron oxide nanoparticles (IONPs) were obtained via synthesis of a monodispersed iron oxide core stabilized with tetramethylammonium hydroxide pentahydrate (TMAOH), followed...
PREMISE OF THE STUDY: We report the de novo assembly and characterization of the transcriptomes of Brachypodium sylvaticum
(slender false-brome) accessions from native populations of Spain and Greece, and an invasive population west of Corvallis,
Oregon, USA.
METHODS AND RESULTS: More than 350 million sequence reads from the mRNA libraries...
This study describes the combined experimental and computational elucidation of the mechanism and
origins of stereoselectivities in the NHC-catalyzed dynamic kinetic resolution (DKR) of α-substituted-β-ketoesters. Density functional theory computations reveal that the NHC-catalyzed DKR proceeds by two
mechanisms, depending on the stereochemistry around the forming bond: 1) a concerted, asynchronous...
Based on regional-scale studies, aboveground production and litter decomposition are thought to positively covary, because they are driven by shared biotic and climatic factors. Until now we have been unable to test whether production and decomposition are generally coupled across climatically dissimilar regions, because we lacked replicated data collected within...
Seed dormancy has played a significant role in adaptation and evolution of seed
plants. While its biological significance is clear, molecular mechanisms underlying seed
dormancy induction, maintenance and alleviation still remain elusive. Intensive efforts
have been made to investigate gibberellin and abscisic acid metabolism in seeds, which
greatly contributed to...
Dietary restriction (DR) is the gold standard intervention used to delay aging, and much recent research has focused on
the identification of possible DR mimetics. Energy sensing pathways, including insulin/IGF1 signaling, sirtuins, and
mammalian Target of Rapamycin (mTOR), have been proposed as pathways involved in the antiaging actions of DR,...
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is consistent with several previous reports (25–27),
a study by Fang and coworkers (28) showed that
The intracellular mutualism between cnidarians and photosynthetic dinoflagellates (genus Symbiodinium) is responsible for the physical and trophic structure of diverse coral reef ecosystems. This relationship, based on nutrient exchange, allows for high productivity in tropical waters, which are generally nutrient-poor environments. Numerous environmental stressors currently threaten the health of corals,...
Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. In this thesis, we studied the formation and modification of the nonproteinogenic amino acid enduracididine (End), which exists in two important antibiotics, mannopeptimycins (MPPs) and enduracidin.
Sequence analysis of the MPP gene cluster revealed that the product of...
In 2008, China released a new green initiative, the Green Securities Policy, to increase the sustainability of Chinese capital markets. One of the integral components of the policy is the new environmental disclosure regulation which prescribes Chinese listed companies in the 14 highly polluting industries to report required environmental information....
Polycyclic aromatic hydrocarbons (PAHs) and oxygen-substituted PAHs (OPAHs) are environmental contaminants present in urban air, dust, soil and water resulting from incomplete combustion of organic materials or fossil fuels; found in crude oil and coal; and formed through photoxidation or biotransformation of microbial. It is widely recognized that PAHs pose...
Heatmap regression has became one of the mainstream approaches to localize facial landmarks. As Convolutional Neural Network (CNN) and Recurrent Neural Network (RNN) are becoming popular in solving computer vision tasks, extensive research has been done on these architectures. However, the loss function for heatmap regression is rarely studied. In...
Hereditary variation is a vital component in the development of new and improved cultivars of landscape plants. Sources of hereditary variation include naturally occurring variation, recombination due to controlled crosses, artificial mutagenesis, and genetic modification via biotechnology. Here I explore all methods with the exception of genetic modification via biotechnology....
Mechanical pulp fibers (MPFs) and chemical pulp fibers (CPFs) from moso bamboo have been characterized in terms of their length and width distributions, and their reinforcing effects in unsaturated polyester (UPE) composites have also been investigated. CPF-UPE composites had much higher tensile strength, flexural strength, and flexural modulus than MPF-UPE...
An increase in anthropogenic activities since the industrial revolution, primarily due to burning of fossil fuels and changes in land cover, has resulted in a steady increase in the global mean atmospheric CO2 concentrations. While there is unequivocal scientific evidence on global warming and its multidimensional impacts on natural and...
Authigenic carbonates and chemosymbiotic biota are archives of seepage 1 history and record paleo-environmental conditions at seep sites. Based on mineral and stable isotope compositions and U/Th-isotope systematics of seep carbonates and Calyptogena sp shell fragments from three seep sites located at 22°02' ~22°09'N, 118°43'~118°52'E (water depths: 473 m to...
Learning to recognize objects is a fundamental and essential step in human perception and understanding of the world. Accordingly, research of object discovery across diverse modalities plays a pivotal role in the context of computer vision. This field not only contributes significantly to enhancing our understanding of visual information but...
Previous investigations have failed to show benefits of low level laser therapy (LLLT) for tendon healing in horses, contrary to reports in other species. We hypothesized that delivery of LLLT at manufacturer-recommended energy fluence through equine cadaver skin to equine tendon-derived fibroblasts in vitro would increase cell proliferation, metabolic activity...
Immature T cells, known as thymocytes, undergo development through successive stages in the thymus and the periphery to become functional mature T cells. These stages are regulated by sequence specific transcription factors (SSTFs). Two such SSTFs, BCL11B and TCF-1, are both known master regulators of thymopoiesis, which is also known...
In the 21st century, environmental deterioration is now an indisputable fact. Reliable and economically viable electricity systems based on renewable sources are urgently needed to replace the environmentally detrimental fossil fuels. The feasibility of incorporating renewable-but-intermittent solar and wind energy heavily depends on the development of cost-effective and safe technologies,...
Different gate length (0.5 μm 16 μm) Al GaAs/GaAs and
AIGaAs /InGaAs High Electron Mobility Transistors were electrically
characterized in order to compare the room temperature DC device
performance with one-dimensional device models. Model parameters
such as the channel mobility and source/drain series resistances are
extracted from independent measurement of...
Studies were conducted to investigate the metabolism of
selenium (Se) , and the influences of Se on the metabolism of cadmium (Cd) and inorganic mercury (Hg) in rats, and in ram semen in
vitro. Se-deficient (-Se) or Se-adequate (+Se) rats were injected intraperitoneally with either ¹⁰⁹CdCl₂ (5 μCi/rat) or ²⁰³HgN0₃...
The development of ecohydrological frameworks and theories under the ongoing global climate crisis depends on the development of new and advanced ecohydrological measurements. Currently, numerous of datasets have been collected at plot and ecosystem levels to understand the complex interactions of along the soil, plant, and atmosphere continuum. The development...
Lepidopteran nucleopolyhedroviruses are members of the Baculoviridae and have been categorized as having two morphotypes of occluded virions: multiple nucleocapsids or single nucleocapsids within the virion envelope. Although it is a definitive characteristic of specific viruses, it appears to lack a defined genetic basis and is independent of virus phylogeny....
Reproductive timing in corals is associated with environmental variables including temperature, lunar periodicity, and
seasonality. Although it is clear that these variables are interrelated, it remains unknown if one variable in particular acts as
the proximate signaler for gamete and or larval release. Furthermore, in an era of global warming,...
Dendrimers are well-defined, polymeric nanomaterials currently being investigated for their biomedical applications. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The objective of the present study was to investigate the role of surface charge and generation...
Diatoms are single-celled algaes that make photonic-crystal-like silica shells or frustules with hierarchical micro- & nano-scale features consisting of two-dimensional periodic pores. This article reports the use of diatom frustules as an integration platform to enhance localized surface plasmon resonances of self-assembled silver nanoparticles (NPs) on the surface of diatom...
Assembly of nanocrystals is considered one of the most promising approaches to design nano-, microstructures, and complex mesoscopic architectures. A variety of strategies to induce nanocrystal assembly have been reported, including directed assembly methods that apply external forces to fabricate assembled structures. In this study ZnO nanocrystals were synthesized in...
Analytical chemistry is an area of chemistry primarily focused on the study and use of instruments for separation, identification, and quantification of an analyte of interest. Specifically, separation science within analytical chemistry often refers to the process of dividing mixtures into their small component parts based on differences in their...
The dissertation focuses on the engineering of light-matter interaction using plasmonic nanoparticles and metamaterials to achieve enhanced luminescence and based on which to improve the performance of biosensing and light-emitting technologies. We designed and fabricated a spectrum of nanostructures to exhibit particular dispersion relations capable of controlling the spontaneous emission...
The continuous development of higher performing battery materials has emerged in parallel with the development of new manufacturing processes. Nanomaterials are one solution to addressing the cycling and performance challenges that limit existing battery cells. However, many of the methods used today for nanomaterial synthesis are high temperature batch methods...
Several plant hormones, including ethylene and jasmonates, are known to mediate responses against biotic and abiotic stress. The first and second objectives of this thesis were (i) to elucidate the role of ethylene in defense responses against Botrytis cinerea and specifically (ii) to determine the potential contribution of ethylene response...
Ample research has demonstrated the largely untapped potential of bioactive peptides (BAPs) for treating systematic chronic inflammation (SCI). Protein hydrolysates are the mixture of peptides resulting from the hydrolytic breakdown of a protein. Numerous hydrolysates contain BAPs and exert beneficial effects in both in vitro and in vivo models. In...
Porous carbon is indispensable in modern technology applications. It is used for energy storage, gas separation, water purification, catalyst support, and chromatography. The diversity of its applications stems from its unique properties, including high specific surface area, tunable pore volume, and chemical stability. Specifically, the large surface area provides high...
In order to better predict the aggregation state of nanomaterials, the factors that influence aggregation must be understood. The combined effects of natural and engineered coatings have been shown to factor into nanoparticle aggregation behavior in preliminary research. In this study, aggregation behaviors of gold nanoparticles with two different engineered...
Influences of operating conditions on the production of carbon nanotubes
(CNTs) were studied using Fe and Fe-Ni bimetallic catalysts supported on silicon
monoxide (SiO). The catalysts were prepared in three steps: (1) impregnation of SiO
powders with ferric nitride or combinations of ferric and nickel nitrides, (2) oxidation
of nitrides...
We demonstrate that unidirectionally aligned, free-standing multi-walled carbon nanotubes (CNTs) exhibit highly anisotropic linear and nonlinear terahertz (THz) responses. For the polarization parallel to the CNT axis, strong THz pulses induce nonlinear absorption in the quasi-one-dimensional conducting media, while no nonlinear effect is observed in the perpendicular polarization configuration. Time-resolved...
A wearable, multi-modal sensor is presented that can non-invasively monitor a patient’s activity level and heart function concurrently for more than a week. The 4in² sensor incorporates both a non-contact heartrate sensor and a 5-axis inertial measurement unit (IMU), allowing simultaneous heart, respiration, and movement monitoring without requiring physical contact...
Sepsis is an inflammatory reaction occurring throughout the human body to infections caused by bacteria, fungi, and or other forms of pathogens. It is essential to find an alternative treatment method for sepsis, to lessen the dependence on antibiotics. Hemoperfusion is an absorbent device that removes select targets from blood,...
The Walla Walla Basin, in Eastern Oregon and Washington, USA, faces challenges in sustaining an agricultural water supply while maintaining sufficient flow in the Walla Walla River for endangered fish populations. Minimum summer river flow of 0.71 m³/s is required, forcing irrigators to substitute groundwater from a declining aquifer for...
Linear wireless sensor networks (LWSN) are special class of wireless sensor networks where sensor nodes are deployed in a straight line. Monitoring industrial pipelines, railroads, tunnels, power lines, and borders are applications of LWSNs. Wireless sensors are tiny devices with limited energy resources; therefore, efficient energy routing in LWSNs is...
Successful crop production depends initially on the availability of high-quality seed. By 2050 global climate change will have influenced crop yields, but will these changes affect seed quality? The present review examines the effects of elevated carbon dioxide (CO₂) and temperature during seed production on three seed quality components: seed...
Buddleja davidii (butterfly bush) is a highly adaptable landscape plant known for pollinator attraction. Unfortunately, it is also regarded as an invasive plant in highly disturbed environments across the globe. It is an invasive species in Oregon, officially classified as a class B noxious weed in 2004. Currently the state...
Improved recovery of cryopreserved meristems and calli from in
vitro currant (Ribes aureum Pursh and R. ciliatum Humb. & Bonpl.) plants
was obtained by two-hour pretreatment with sucrose, proline, abscisic
acid-responsive protein (RABP), and bovine serum albumin (BSA)
solutions. Meristems and calli cold-acclimatized for one week were
immersed in pretreatment...
Many miles of roads are built in the Pacific Northwest Forests to provide access for logging and fire protection. Logging roads often cross steep mountainous terrain. Logging roads and the associated cut and fill slopes represent a discontinuity in the natural stress state in the soil mantle. These conditions result...
Polycomb Repressive Complex 2 (PRC2) function and DNA methylation (DNAme) are typically correlated with gene repression. Here, we show that PRC2 is required to maintain expression of maternal microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) from the Gtl2-Rian-Mirg locus, which is essential for full pluripotency of iPSCs. In the absence...
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REFERENCES
Chen, X., Xu, H., Yuan, P., Fang, F., Huss, M., Vega, V.B., Wong, E., Orlov, Y.L.,
Zhang, W
Tree mortality is an important demographic process and primary driver of forest dynamics, yet there are relatively few plot-based studies that explicitly quantify mortality and compare the relative contribution of endogenous and exogenous disturbances at regional scales. We used repeated observations on 289,390 trees in 3673 1 ha plots on...
The process of plant speciation often involves the evolution of divergent ecotypes in
response to differences in soil water availability between habitats. While the same set of traits
is frequently associated with xeric/mesic ecotype divergence, it is unknown whether those
traits evolve independently or if they evolve in tandem as...
We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...
The integration of low-pressure membrane filtration and aerobic granular sludge (AGS) reactor leads to a novel environmental biotechnological process with strong potential to overcome membrane fouling and demonstrate excellent wastewater treatment performance. However, membrane fouling mechanisms in the AGS based membrane bioreactor (MBR) are lack of systematic elaboration. In the...
Stripe rust (Puccinia striiformis f. sp. tritici) and Septoria tritici blotch (Zymoseptoria tritici) are a constant and significant threat to wheat production, significantly reducing wheat quality and yield. Wheat is responsible for 20% of the world’s human calorie intake, and wheat production must increase to supply the demand of the...
Cnidarians, such as anemones and corals, engage in an intracellular symbiosis with
photosynthetic dinoflagellates. Corals form both the trophic and structural foundation of
reef ecosystems. Despite their environmental importance, little is known about the
molecular basis of this symbiosis. In this dissertation we explored the cnidariandinoflagellate symbiosis from two perspectives:...
Periodic metal and metal-dielectric composite nanostructures have been of interest from the field of plasmonics and metamaterial fabrication. In order to exploit the behavior of these unique materials in the visible region of the optical spectrum, these structures need to be significantly shorter than the wavelength of response, and hence...
This dissertation focuses on the application of diatom frustules, the biosilica shell of an algae possessing physical and photonic properties capable of enhancing optical signals, for the enhancement of optical sensing. In this work, we incorporate diatom frustules into biosensors for signal enhancement and improved target molecule detection. The potential...
This thesis examines the influence of Christian missions on Yung Wing (1828-1912) during the nineteenth century, when China was beginning to encounter the West. Yung was the first Chinese graduate student to enter an American institution of higher education (Yale College, 1854). As a Westernized Christian intellectual, he strove to...
There has been a tremendous growth in interest in carbon nanodots (C-dots) in the past several years. As a nascent nanomaterial, C-dots have shown great promise in applications that benefit from their superior water dispersibility, low toxicity, non-blinking fluorescent output, chemical and biological compatibility, ease of functionalization and resistance to...
In this article, we price American options under Heston's stochastic volatility model using a radial basis function (RBF) with partition of unity method (PUM) applied to a linear complementary formulation of the free boundary partial differential equation problem. RBF-PUMs are local meshfree methods that are accurate and flexible with respect...
Recent studies have indicated that nickel gallium alloys can be effective for the catalytic hydrogenation of CO2 to methanol. To simplify the characterization of NiGa catalysts, we are developing model systems using NiGa thin films. We prepared NiGa thin films by RF magnetron sputtering using an equiatomic alloy target, followed...
Organic semiconductors are of interest for (opto)electronic applications due to their low cost, solution processability, and tunable properties. Natural product-derived organic pigments have attracted attention due to their extraordinary environmental stability and unexpectedly good optoelectronic performance, in spite of only partially conjugated molecular structures. Fungi-derived pigments are a naturally sourced,...
High vegetative growth of Pinot Noir vine is a common problem in most vineyards of Oregon's Willamette Valley, where sunlight exposure and heat accumulation are limited. Consequently, growers in this region commonly use vineyard management strategies to regulate vine vigor and improve grape and wine quality. Wine quality is greatly...
Deep foundations are necessary for the construction of many structures, such as bridges and buildings, located in areas unsuitable for shallow foundations. Owing to the inherent variability of soil and the complex changes that occur in the soil adjacent to deep foundations as they are installed, the ability to accurately...
Radiation exposure to the brain can occur from a variety of events, including space missions, nuclear accidents, and clinical treatments. The effects of high dose radiation are well studied, but those of lower dosage are more elusive. Decline of memory and cognition is observed in patients exposed to low dose...
The production of titanium dioxide (TiO2) nanoparticles has increased significantly in the past decades, which has generated concern due to their known toxicity in the environment. As a result of the production, use and disposal of productions containing TiO2, TiO2 nanoparticles are often received by wastewater treatment facilities. The adsorption...
In this comprehensive thesis, we present a series of experiments and findings that highlight the
critical importance of TDC Voltage Sensors in the hardware security domain. Our research begins
by introducing a novel self-calibrating module, demonstrating its efficiency through preliminary
calibration tests. We then delve into the Peak-to-Peak tests, which...
The interactions between microbial taxa have been under great research interest in the sci- ence community given the microbiome data deluge. Several methods have been proposed to model and estimate the conditional dependency between microbial taxa for their interac- tions, in order to eliminate spurious correlation detections. However, these methods...
This paper explores the use of sonification, the conversion of data into sound, to convey the significance of SARS-COV-2 and its global impact. It emphasizes sonification as a valuable tool for making complex data accessible, particularly in high school education. Sonification, an interdisciplinary field, leverages the human auditory system's pattern...
A continuous flow sonochemical reactor was developed capable of producing metastable cadmium sulfide (CdS) nanoplatelets with thicknesses at or below 10 nm. The continuous flow sonochemical reactor included the passive in-line micromixing of reagents prior to sonochemical reaction. Synthesis results were compared with those from reactors involving batch conventional heating...
The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
Whole ecosystem carbon dioxide (CO₂) exchange estimated with the eddy covariance (EC) technique has been central to studies on the responses of terrestrial ecosystems to disturbance and intra‐annual and interannual variations in climate, but challenges exist in understanding and reducing the uncertainty in estimates of net ecosystem exchange (NEE) of...
Over the last several decades, potato production has increased globally as it has been recognized as an important component to improving food security. However, potato production has been continuously challenged by pests. Current pest management practices rely heavily on chemical pesticides. Unfortunately, the overuse of pesticides can be harmful to...
When people talk about the one-child policy in China, it always relates to topics like human rights violations or the population control dilemma. The one-child policy was published in the 1980s, around the same time as the Economic Reform, and these twin policies brought Chinese society tremendous changes. This paper...
Abstract Endogenous levels and signaling of gibberellin plant hormones such as
gibberellic acid (GA) have been genetically down-regulated to create semi-dwarf
varieties of poplar. The potential benefits of semi-dwarf stature include reduced risk of
wind damage, improved stress tolerance, and improved wood quality. Despite these
benefits, modification of growth traits...
This work presents improvements to a multi-core performance/power simulator. The improvements which include updated power models, voltage scaling aware models, and an application specific benchmark, are done to increase the accuracy of power models under voltage and frequency scaling. Improvements to the simulator enable more accurate design space exploration for...
"This report concerns one aspect of the marina permit evaluation process: water quality impacts related to marina circulation and flushing efficiency. These physical properties vary with the wind, tide range, water density and physical dimensions of a marina. Water quality is affected by the degree of flushing, and sediment redistribution...
Sulforaphane is an isothiocyanate derived from cruciferous vegetables and has been under investigation as a cancer chemopreventive agent for over two decades. The compound is well tolerated and has been shown to slow cancer progression in several different pre-clinical models of carcinogenesis, such as of the lung, breast and colon....
Wicking action refers to the movement of a liquid through a porous or a structured surface via capillary action. This phenomenon is affected by surface geometry, such as the wick thickness and pore size of the wick, as well as fluid properties, such as viscosity and surface tension of the...
Hemp is a dioecious, annual, flowering plant in the Cannabaceae family. It has been used for thousands of years to produce textiles, essential oils, and medicines. The overall purpose of these experiments was to propagate the cannabinoid-free cultivar, ‘I3’, and follow up by inducing polyploidy in the ‘I3’ hemp via...
Vibrio parahaemolyticus is a foodborne pathogen recognized as the leading cause of acute gastroenteritis associated with consumption of raw and undercooked seafood, particularly raw oysters, with major symptoms of nausea, vomiting, abdominal cramps and diarrhea. It is estimated that 45,000 cases of V. parahaemolyticus infection occur each year in the...
Cnidarians, such as corals and sea anemones serve as hosts to a variety of organisms including symbiotic dinoflagellates, bacteria, virus, and apicomplexans. As corals are vital to the health and productivity of the reef ecosystem it is important to understand how these organisms interact with each component of the holobiont....
High Entropy Alloys (HEA) exhibit unusual properties and are gaining interest as new materials for challenging applications in the aerospace, hypersonic and medical fields. The application of HEAs have been limited by the development of powder production at scale. A recently developed process of plasma spheroidization by 6K, inc. has...
Pesticides benefit agriculture by increasing crop yield, quality, and security. However, pesticides may inadvertently harm bees, which are valuable as pollinators. Thus, candidate pesticides in development pipelines must be assessed for toxicity to bees.
Leveraging a data set of 382 molecules with toxicity labels from honey bee exposure experiments, we...
In the past two decades, the advancement in data collection and storage have led to the accumulation of complex datasets. Consequently, various industries have sought data-driven solutions to predict and detect anomalies. Temporal patterns have emerged as potential features in prediction models that could improve the performance of the identification...
Per- and polyfluoroalkyl substances (PFAS) are anthropogenic surfactants that have recently been identified as persistent organic pollutants. These so called “Forever Chemicals” have been detected in drinking waters, ground waters, soils, and consumer and industrial products globally; with environmental impacts stretching into the artic, far from known PFAS sources. The...
Zinc is an important micronutrient involved in many cellular processes, including those part of immune function; however, about 15% of the US population is at risk for marginal zinc deficiency. This can lead to immune system complications including the generation of inflammatory cytokines. Aging is another factor that worsens the...
Cancer is currently the second leading cause of death in the United States and the sixth leading cause of death worldwide. Due to cancer’s variability in type, location, growth rates, and patient physiology, treatment models are based off of previous experimental and clinical work. This variability, however, can lead to...
Dendrimers are well-defined, polymeric nanomaterials currently being investigated for biomedical applications such as medical imaging, gene therapy, and tissue targeted therapy. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The majority of studies exploring dendrimer toxicity...
The motivation for undertaking this research was to increase the understanding of processing colloidal semiconductor nanocrystals and thin films metallic glasses to enable their wider application in future devices. This research covered two unique materials, lead selenide (PbSe) nanocrystals and thin film metallic glass alloy of zirconium copper aluminum nickel...
Early childhood is a crucial time for the holistic development of a child’s social, emotional, cognitive, and physical needs to build a solid and broad foundation for lifelong wellbeing and learning (Irwin et al., 2007). During this critical period, there is an increased demand for motor skills and executive function...